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Titolo:
Locomotor-stimulating effects of indirect dopamine agonists are attenuatedin Fawn hooded rats independent of postweaning social experience
Autore:
Hall, FS; Fong, GW; Ghaed, S; Pert, A;
Indirizzi:
NIAAA, DICBR, Clin Studies Lab, Bethesda, MD 20892 USA NIAAA Bethesda MD USA 20892 CBR, Clin Studies Lab, Bethesda, MD 20892 USA Univ Maryland, Dept Psychol, College Pk, MD 20742 USA Univ Maryland College Pk MD USA 20742 t Psychol, College Pk, MD 20742 USA NIMH, Biol Psychiat Branch, Bethesda, MD 20892 USA NIMH Bethesda MD USA 20892 , Biol Psychiat Branch, Bethesda, MD 20892 USA
Titolo Testata:
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
fascicolo: 3-4, volume: 69, anno: 2001,
pagine: 519 - 526
SICI:
0091-3057(200107/08)69:3-4<519:LEOIDA>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALCOHOL-PREFERRING RATS; VENTRAL TEGMENTAL AREA; ELEVATES EXTRACELLULAR DOPAMINE; VOLUNTARY ETHANOL INTAKE; AVOIDING ANA RATS; NUCLEUS-ACCUMBENS; BEHAVIORAL-RESPONSES; ACOUSTIC STARTLE; LABORATORY RATS; WISTAR RATS;
Keywords:
isolation rearing; Fawn hooded rats; dopamine; cocaine; amphetamine;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
67
Recensione:
Indirizzi per estratti:
Indirizzo: Hall, FS Natl Inst Drug Abuse, IRP, Mol Neurobiol Branch, POB 5180,5500 Nathan Shock Dr, Baltimore, MD 21224 USA Natl Inst Drug Abuse POB 5180,5500 Nathan Shock Dr Baltimore MD USA 21224
Citazione:
F.S. Hall et al., "Locomotor-stimulating effects of indirect dopamine agonists are attenuatedin Fawn hooded rats independent of postweaning social experience", PHARM BIO B, 69(3-4), 2001, pp. 519-526

Abstract

The effects of the indirect dopamine (DA) agonists cocaine and D-amphetamine on locomotor activity were examined in Fawn hooded (FH) rats and Wistar rats. The effect of isolation rearing was also examined to determine if it might have different effects in these two strains. Contrary to previous findings in other rat strains, only small increases in locomotor-stimulating responses to low doses of cocaine were observed in the present study as a result of isolation rearing. However, at higher cocaine doses, locomotor activity was substantially attenuated in FH rats relative to Wistar rats. A similar pattern of effects was observed for amphetamine in FH rats but only atthe intermediate dose. The effects of strain and rearing were independent. There was no evidence for interactions between these factors. (C) 2001 Elsevier Science Inc. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/01/20 alle ore 01:00:43