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Titolo:
Orofacial effects of antiretroviral therapies
Autore:
Scully, C; Dios, PD;
Indirizzi:
Univ Coll London, Int Ctr Excellence Dent, London WC1X 8LD, England Univ Coll London London England WC1X 8LD Dent, London WC1X 8LD, England Univ Coll London, Eastman Dent Inst Oral Hlth Care Sci, London WC1X 8LD, England Univ Coll London London England WC1X 8LD e Sci, London WC1X 8LD, England Univ Santiago de Compostela, Sch Med & Dent, Santiago De Compostela, SpainUniv Santiago de Compostela Santiago De Compostela Spain postela, Spain
Titolo Testata:
ORAL DISEASES
fascicolo: 4, volume: 7, anno: 2001,
pagine: 205 - 210
SICI:
1354-523X(200107)7:4<205:OEOAT>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
HUMAN-IMMUNODEFICIENCY-VIRUS; PROTEASE INHIBITOR THERAPY; HIV-INFECTED PATIENTS; COMBINATION THERAPY; CUBIC MILLIMETER; CONTROLLED TRIAL; OROPHARYNGEAL CANDIDIASIS; CYTOMEGALOVIRUS RETINITIS; CHANGING PREVALENCE; ORAL MANIFESTATIONS;
Keywords:
HIV; oral; antiretroviral;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
72
Recensione:
Indirizzi per estratti:
Indirizzo: Scully, C Univ Coll London, Int Ctr Excellence Dent, 256 Grays Inn Rd, London WC1X 8LD, England Univ Coll London 256 Grays Inn Rd London England WC1X 8LD gland
Citazione:
C. Scully e P.D. Dios, "Orofacial effects of antiretroviral therapies", ORAL DIS, 7(4), 2001, pp. 205-210

Abstract

This paper summarises some of the oral adverse effects of antiretroviral agents. Some are related to bone marrow suppression which may also predispose to mouth ulcers. Erythema multiforme and toxic epidermal necrolysis are especially well recognized in HIV disease, particularly as reactions to sulphonamides and to antiretroviral agents. Oral lichenoid reactions have been described in HIV disease often relating to zidovudine use. Didanosine has also produced erythema multiforme and not unusually induces xerostomia, again by an unknown mechanism. Xerostomia may be seen in up to one-third of patients taking didanosine. Taste abnormalities are common with the protease inhibitors and oral and perioral paraesthesia can be a disturbing adverse effect. Ritonavir in particular can give rise to circumoral paraesthesia in over 25% of patients. Indinavir can also produce cheilitis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 00:44:57