Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
DNA replication origins: from sequence specificity to epigenetics
Autore:
Mechali, M;
Indirizzi:
CNRS, Inst Human Genet, F-34396 Montpellier, France CNRS Montpellier France F-34396 Human Genet, F-34396 Montpellier, France
Titolo Testata:
NATURE REVIEWS GENETICS
fascicolo: 8, volume: 2, anno: 2001,
pagine: 640 - 645
SICI:
1471-0056(200108)2:8<640:DROFSS>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
BETA-GLOBIN LOCUS; RECOGNITION COMPLEX FUNCTIONS; SACCHAROMYCES-CEREVISIAE; YEAST ORIGIN; CONTROL REGION; RIBOSOMAL DNA; START SITES; CHROMATIN; INITIATION; TRANSCRIPTION;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
74
Recensione:
Indirizzi per estratti:
Indirizzo: Mechali, M CNRS, Inst Human Genet, 141 Rue Cardonille, F-34396 Montpellier, France CNRS 141 Rue Cardonille Montpellier France F-34396 ier, France
Citazione:
M. Mechali, "DNA replication origins: from sequence specificity to epigenetics", NAT REV GEN, 2(8), 2001, pp. 640-645

Abstract

Site-specific initiation of DNA replication is a conserved function in allorganisms. In Escherichia coli and Saccharomyces cerevisiae. DNA replication origins are sequence specific, but in multicellular organisms, origins are not so clearly defined. In this article, I present a model of origin specification by epigenetic mechanisms that allows the establishment of stablechromatin domains, which are characterized by autonomous replication. According to this model, origins of DNA replication help to establish domains of gene expression for the generation of cell diversity.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 07:10:07