Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Cloning and developmental expression of STAT5 in Xenopus laevis
Autore:
Pascal, A; Riou, JF; Carron, C; Boucaut, JC; Umbhauer, M;
Indirizzi:
Univ Paris 06, CNRS, UMR 7622, Grp Biol Expt,Lab Biol Mol & Cellulaire Dev, F-75005 Paris, France Univ Paris 06 Paris France F-75005 Cellulaire Dev, F-75005 Paris, France
Titolo Testata:
MECHANISMS OF DEVELOPMENT
fascicolo: 1-2, volume: 106, anno: 2001,
pagine: 171 - 174
SICI:
0925-4773(200108)106:1-2<171:CADEOS>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
ACTIVATION; EMBRYOS; HYBRIDIZATION; PROTEINS;
Keywords:
Xenopus laevis; embryogenesis; STAT5; eye; pineal glands; neural plate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Umbhauer, M Univ Paris 06, CNRS, UMR 7622, Grp Biol Expt,Lab Biol Mol & Cellulaire Dev, 9 Quai St Bernard, F-75005 Paris, France Univ Paris 06 9 QuaiSt Bernard Paris France F-75005 , France
Citazione:
A. Pascal et al., "Cloning and developmental expression of STAT5 in Xenopus laevis", MECH DEVEL, 106(1-2), 2001, pp. 171-174

Abstract

Transcription factors of the signal transducer and activator of transcription (STAT) family are required for cellular responses to multiple signalling molecules. After ligand binding-induced activation of cognate receptors, STAT proteins are phosphorylated, hetero- or homodimerize, and enter the nucleus. STAT dimers bind to specific DNA elements and alter the transcriptional activity of the signal-responsive genes. We report the cloning and developmental pattern of expression of XSTAT5, a Xenopus laevis member of the STAT family, closely related to the mammalian STAT5A and STAT5B. XSTAT5 is expressed maternally and zygotically. With the onset of neurulation, XSTAT5 RNA are clearly localized in the anterior neural plate and subsequently in the neural structures of the developing eye, the pineal g-land and the cement gland anlage, At late tailbud stages, a faint expression is detected in a ventral location that might correspond to the ventral blood islands. (C) 2001 Elsevier Science Ireland Ltd. Ail rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 14:21:39