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Titolo:
Shh and Ptc are associated with taste bud maintenance in the adult mouse
Autore:
Miura, H; Kusakabe, Y; Sugiyama, C; Kawamatsu, M; Ninomiya, Y; Motoyama, J; Hino, A;
Indirizzi:
Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan Natl Food Res Inst Tsukuba Ibaraki Japan 3058642 , Ibaraki 3058642, Japan Kyushu Univ, Fac Dent, Higashi Ku, Fukuoka 8128582, Japan Kyushu Univ Fukuoka Japan 8128582 nt, Higashi Ku, Fukuoka 8128582, Japan Bio Orineted Technol Res Advancement Inst, Minato Ku, Tokyo 105, Japan BioOrineted Technol Res Advancement Inst Tokyo Japan 105 kyo 105, Japan RIKEN, Inst Phys & Chem Res, Brain Sci Inst, Mol Neuropathol Grp, Wako, Saitama 3510198, Japan RIKEN Wako Saitama Japan 3510198 pathol Grp, Wako, Saitama 3510198, Japan
Titolo Testata:
MECHANISMS OF DEVELOPMENT
fascicolo: 1-2, volume: 106, anno: 2001,
pagine: 143 - 145
SICI:
0925-4773(200108)106:1-2<143:SAPAAW>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
RAT CIRCUMVALLATE; SONIC HEDGEHOG; PAPILLAE; EXPRESSION; CONSERVATION; INDUCTION; RENEWAL;
Keywords:
taste bud; tongue; taste nerve; Sonic hedgehog; patched1; adult mouse;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
11
Recensione:
Indirizzi per estratti:
Indirizzo: Miura, H Natl Food Res Inst, 2-1-12 Kannondai, Tsukuba, Ibaraki 3058642, Japan Natl Food Res Inst 2-1-12 Kannondai Tsukuba Ibaraki Japan 3058642
Citazione:
H. Miura et al., "Shh and Ptc are associated with taste bud maintenance in the adult mouse", MECH DEVEL, 106(1-2), 2001, pp. 143-145

Abstract

In mammals, taste receptor cells are organized into taste buds on tongue. Taste buds are trophically maintained by taste neurons and under continuousrenewal, even in adults. We found that the receptor for Sonic hedgehog (Shh), Patched1 (Ptc), was expressed around taste buds where cells were proliferating, and that Shh was expressed within basal cells of taste buds. Denervation caused the loss of Shh and Ptc expression before the degeneration oftaste buds. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 09:10:50