Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Risk factors for liver abscess formation after hepatic chemoembolization
Autore:
Kim, W; Clark, TWI; Baum, RA; Soulen, MC;
Indirizzi:
Univ Penn, Sch Med, Hosp Univ Penn, Div Intervent Radiol, Philadelphia, PA19104 USA Univ Penn Philadelphia PA USA 19104 ent Radiol, Philadelphia, PA19104 USA
Titolo Testata:
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
fascicolo: 8, volume: 12, anno: 2001,
pagine: 965 - 968
SICI:
1051-0443(200108)12:8<965:RFFLAF>2.0.ZU;2-H
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRANSCATHETER ARTERIAL CHEMOEMBOLIZATION; PERCUTANEOUS DRAINAGE; HEPATOCELLULAR-CARCINOMA; COMPLICATIONS; MANAGEMENT; TUMORS; EMBOLIZATION; ASPIRATION; SURVIVAL;
Keywords:
chemoembolization; liver, abscess; liver neoplasms, chemotherapeutic infusion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
36
Recensione:
Indirizzi per estratti:
Indirizzo: Soulen, MC Univ Penn, Sch Med, Hosp Univ Penn, Div Intervent Radiol, 3400 Spruce St, Philadelphia, PA 19104 USA Univ Penn 3400 Spruce St PhiladelphiaPA USA 19104 PA 19104 USA
Citazione:
W. Kim et al., "Risk factors for liver abscess formation after hepatic chemoembolization", J VAS INT R, 12(8), 2001, pp. 965-968

Abstract

PURPOSE: To assess the frequency and risk factors for liver abscess after hepatic chemoembolization. MATERIALS AND METHODS: The authors performed retrospective analysis of 397chemoembolization procedures in 157 patients. All patients received prophylactic intravenous antibiotics before the procedure and 5 days of oral antibiotics after the procedure. The association between abscess formation and risk factors was determined with use of chi (2) analysis and the Fisher exact test and expressed as an odds ratio. RESULTS: Liver abscess occurred in seven of 157 patients (4.5%) after eight of 397 procedures (2.0%) at a mean of 19 d +/- 7 after chemoembolization. No patients had neutropenia. Organisms isolated reflected intestinal flora. Six patients required percutaneous drainage for 35 d +/- 29. The seventh patient required drainage for the remainder of life as a result of a nonhealing biliary fistula. Three of 24 patients with neuroendocrine tumors had abscesses (12.5%; odds ratio, 4.6; 95% CI, 0.96-22.1; P = .07), as did threeof 14 patients with gastrointestinal sarcomas (21%; odds ratio, 9.5; 95% CI, 1.9-47.8; P = .016), and one of two with pancreatic adenocarcinoma. Six of the seven patients with abscesses underwent a Whipple procedure before chemoembolization. Only one patient with a history of a Whipple procedure did not develop an hepatic abscess. In the absence of a bilioenteric anastomosis, abscess occurred in only one of 150 patients (0.7%), or one of 383 procedures (0.3%). The odds ratio for liver abscess among patients with a bilioenteric anastomosis was 894 (95% CI, 50-16,000; P < .0001). CONCLUSION: Earlier bilioenteric anastomosis is the major determinant of liver abscess formation after hepatic chemoembolization. The prophylaxis regimen used failed to prevent abscess formation in patients with earlier bilioenteric anastomosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 15:23:27