Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Anticipation of increasing monetary reward selectively recruits nucleus accumbens
Autore:
Knutson, B; Adams, CM; Fong, GW; Hommer, D;
Indirizzi:
NIAAA, NIH, Bethesda, MD 20892 USA NIAAA Bethesda MD USA 20892NIAAA, NIH, Bethesda, MD 20892 USA
Titolo Testata:
JOURNAL OF NEUROSCIENCE
fascicolo: 16, volume: 21, anno: 2001,
pagine: NIL_1 - NIL_5
SICI:
0270-6474(20010815)21:16<NIL_1:AOIMRS>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
BRAIN ACTIVITY; HUMAN AMYGDALA; BASAL GANGLIA; DOPAMINE; FMRI; ACTIVATION; MONKEY; VISUALIZATION; RESPONSES; STRIATUM;
Keywords:
nucleus accumbens; caudate; reward; anticipation; FMRI; human;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Knutson, B NIAAA, NIH, Bldg 10,Room 6S240,MS 1610, Bethesda, MD 20892 USA NIAAA Bldg 10,Room 6S240,MS 1610 Bethesda MD USA 20892 0892 USA
Citazione:
B. Knutson et al., "Anticipation of increasing monetary reward selectively recruits nucleus accumbens", J NEUROSC, 21(16), 2001, pp. NIL_1-NIL_5

Abstract

Comparative studies have implicated the nucleus accumbens (NAcc) in the anticipation of incentives, but the relative responsiveness of this neural substrate during anticipation of rewards versus punishments remains unclear. Using event-related functional magnetic resonance imaging, we investigated whether the anticipation of increasing monetary rewards and punishments would increase NAcc blood oxygen level-dependent contrast (hereafter, "activation") in eight healthy volunteers. Whereas anticipation of increasing rewards elicited both increasing self-reported happiness and NAcc activation, anticipation of increasing punishment elicited neither. However, anticipationof both rewards and punishments activated a different striatal region (themedial caudate). At the highest reward level ($5.00), NAcc activation was correlated with individual differences in self-reported happiness elicited by the reward cues. These findings suggest that whereas other striatal areas may code for expected incentive magnitude, a region in the NAcc codes forexpected positive incentive value.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/09/20 alle ore 09:24:40