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Titolo:
Evaluation of tiapride in agitated elderly outpatients: an open study
Autore:
Tsolaki, M;
Indirizzi:
Aristotelian Univ Thessaloniki, Salonika 54621, Greece Aristotelian Univ Thessaloniki Salonika Greece 54621 onika 54621, Greece
Titolo Testata:
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL
fascicolo: 5, volume: 16, anno: 2001,
pagine: 417 - 422
SICI:
0885-6222(200107)16:5<417:EOTIAE>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
ALZHEIMERS-DISEASE; BEHAVIORAL SYMPTOMS; RATING-SCALE; DEMENTIA; RISPERIDONE; HALOPERIDOL; PLACEBO; TRIAL;
Keywords:
agitation; tiapride; elderly;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Tsolaki, M Aristotelian Univ Thessaloniki, Despere 3, Salonika 54621, Greece Aristotelian Univ Thessaloniki Despere 3 Salonika Greece 54621
Citazione:
M. Tsolaki, "Evaluation of tiapride in agitated elderly outpatients: an open study", HUM PSYCHOP, 16(5), 2001, pp. 417-422

Abstract

The aim of this study was the evaluation of the efficacy and safety of tiapride 50-100 mg administered 3 times a day to elderly patients with aggressive behavior. Data from 425 questionnaires concerning aggressive behavior in Greek elderly patients were evaluated before and after treatment. The Brief Agitation Rating Scale (BARS), which has 10 items, was used to evaluate the effectiveness of tiapride. To test the overall effectiveness of the drug during the trial, the statistical method of repeated measures ANOVA was applied to the total score and the very small F-value (p < 0.0005) led us toaccept the hypothesis that tiapride significantly improves the condition of elderly patients with aggressive behavior. Only 6.2% of patients developed an adverse event during the trial. With 95% probability one may state that the probability of an adverse event occurring during the administration of tiapride is between 5% and 7.4%. We conclude that tiapride, apart from being very efficient in ameliorating aggressive behavior in elderly patients,is also very safe to administer. Copyright <(c)> 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 18/01/20 alle ore 10:46:38