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Titolo:
Glomerulonephritis associated with deficiencies and polymorphisms of complement components encoded in the class III region of the MHC
Autore:
Welch, TR; Frenzke, M;
Indirizzi:
Childrens Hosp Res Fdn, Div Nephrol & Hypertens, Cincinnati, OH 45229 USA Childrens Hosp Res Fdn Cincinnati OH USA 45229 , Cincinnati, OH 45229 USA Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA Univ Cincinnati Cincinnati OH USA l Med, Dept Pediat, Cincinnati, OH USA
Titolo Testata:
FRONTIERS IN BIOSCIENCE
, volume: 6, anno: 2001,
pagine: D898 - D903
SICI:
1093-9946(200108)6:<D898:GAWDAP>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAJOR-HISTOCOMPATIBILITY-COMPLEX; IDIOPATHIC MEMBRANOUS NEPHROPATHY; SYSTEMIC LUPUS-ERYTHEMATOSUS; HENOCH-SCHONLEIN PURPURA; IGA NEPHROPATHY; C4B DEFICIENCY; 4TH COMPONENT; RECURRENT INFECTIONS; GENETIC DEFICIENCY; CONTROL PROTEINS;
Keywords:
complement; glomerulonephritis; deficiency; MHC; review;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
48
Recensione:
Indirizzi per estratti:
Indirizzo: Welch, TR Childrens Hosp, Med Ctr, 3333 Burnet Ave,TCHRF5, Cincinnati, OH 45229 USA Childrens Hosp 3333 Burnet Ave,TCHRF5 Cincinnati OH USA 45229 SA
Citazione:
T.R. Welch e M. Frenzke, "Glomerulonephritis associated with deficiencies and polymorphisms of complement components encoded in the class III region of the MHC", FRONT BIOSC, 6, 2001, pp. D898-D903

Abstract

An association between the complement system and immune complex glomerulardisease in humans has long been recognized. In fact, much of our early understanding of the immunochemistry of complement activation developed with the study of acute and chronic glomerulonephritis (1). This manuscript will examine associations between glomerulonephritis and the three complement components encoded within the major histocompatibility complex: C4, C2, and factor B (B). The mechanisms by which deficiencies or polymorphisms in thesecomponents can mediate disease will be examined.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/09/20 alle ore 08:58:09