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Titolo:
Fractal analyses of osseous healing using Tuned Aperture Computed Tomography images
Autore:
Nair, MK; Seyedain, A; Webber, RL; Nair, UP; Piesco, NP; Agarwal, S; Mooney, MP; Grondahl, HG;
Indirizzi:
Univ Pittsburgh, Sch Dent Med, Dept Oral & Maxillofacial Radiol, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 Radiol, Pittsburgh, PA 15261 USA Univ Pittsburgh, Sch Dent Med, Dept Periodont, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 riodont, Pittsburgh, PA 15261 USA Wake Forest Univ, Sch Med, Dept Dent, Winston Salem, NC 27101 USA Wake Forest Univ Winston Salem NC USA 27101 , Winston Salem, NC 27101 USA Univ Pittsburgh, Sch Dent Med, Dept Oral Biol, Pittsburgh, PA 15261 USA Univ Pittsburgh Pittsburgh PA USA 15261 al Biol, Pittsburgh, PA 15261 USA Univ Gothenburg, Fac Odontol, Dept Oral & Maxillofacial Radiol, S-40530 Gothenburg, Sweden Univ Gothenburg Gothenburg Sweden S-40530 ol, S-40530 Gothenburg, Sweden
Titolo Testata:
EUROPEAN RADIOLOGY
fascicolo: 8, volume: 11, anno: 2001,
pagine: 1510 - 1515
SICI:
0938-7994(2001)11:8<1510:FAOOHU>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEPTH DISCRIMINATION; RECURRENT CARIES; OSTEOPOROSIS; BONE; RADIOGRAPHS; PROJECTIONS; TACT(TM); LOCATION; GEOMETRY; ACCURACY;
Keywords:
computed tomography; fractal dimension; digital image processing; osseous;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Nair, MK G-120 Salk Hall,3501 Terrace St, Pittsburgh, PA 15261 USA G-120 Salk Hall,3501 Terrace St Pittsburgh PA USA 15261 5261 USA
Citazione:
M.K. Nair et al., "Fractal analyses of osseous healing using Tuned Aperture Computed Tomography images", EUR RADIOL, 11(8), 2001, pp. 1510-1515

Abstract

The aim of this study was to evaluate osseous healing in mandibular defects using fractal analyses on conventional radiographs and tuned aperture computed tomography (TACT; OrthoTACT, Instrumentarium Imaging, Helsinki, Finland) images. Eighty test sites on the inferior margins of rabbit mandibles were subject to lesion induction and treated with one of the following: no treatment (controls); osteoblasts only; polymer matrix only; or osteoblast-polymer matrix (OPM) combination. Images were acquired using conventional radiography and TACT, including unprocessed TACT (TACT-U) and iteratively restored TACT (TACT-IR). Healing was followed up over time and images acquiredat 3, 6, 9, and 12 weeks post-surgery. Fractal dimension (FD) was computedwithin regions of interest in the defects using the TACT workbench. Results were analyzed for effects produced by imaging modality, treatment modality, time after surgery and lesion location. Histomorphometric data were available to assess ground truth. Significant differences (p < 0.0001) were noted based on imaging modality with TACT-IR recording the highest mean fractal dimension (MFD), followed by TACT-U and conventional images, in that order. Sites treated with OPM recorded the highest MFDs among all treatment modalities (p < 0.0001). The highest MFD based on time was recorded at 3 weeksand differed significantly with 12 weeks (p < 0.035). Correlation of FD with results of histomorphometric data was high (r = 0.79; p < 0.001). The FDcomputed on TACT-IR showed the highest correlation with histomorphometric data, thus establishing the fact TACT is a more efficient and accurate imaging modality for quantification of osseous changes within healing bony defects.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 11/07/20 alle ore 07:47:03