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Titolo:
Changes in the utilisation of lipid-lowering drugs over a 6-year period (1993-1998) in a Danish population
Autore:
Larsen, J; Andersen, M; Kragstrup, J; Gram, LF;
Indirizzi:
Univ So Denmark, Res Unit Gen Practice, DK-5000 Odense C, Denmark Univ So Denmark Odense Denmark C Gen Practice, DK-5000 Odense C, Denmark Univ So Denmark, Dept Clin Pharmacol, DK-5000 Odense, Denmark Univ So Denmark Odense Denmark DK-5000 harmacol, DK-5000 Odense, Denmark
Titolo Testata:
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
fascicolo: 4, volume: 57, anno: 2001,
pagine: 343 - 348
SICI:
0031-6970(200107)57:4<343:CITUOL>2.0.ZU;2-2
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; CHOLESTEROL LEVELS; PRAVASTATIN; PREVENTION; FINLAND; HEALTH; TRENDS; AGENTS;
Keywords:
lipid-lowering drug utilisation; statins; prescription database;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Larsen, J Univ So Denmark, Res Unit Gen Practice, Winslowpk 19,3, DK-5000 Odense C, Denmark Univ So Denmark Winslowpk 19,3 Odense Denmark C ense C, Denmark
Citazione:
J. Larsen et al., "Changes in the utilisation of lipid-lowering drugs over a 6-year period (1993-1998) in a Danish population", EUR J CL PH, 57(4), 2001, pp. 343-348

Abstract

Objective: The effect of lipid-lowering drugs (LLDs) on coronary heart disease is well established. However, their utilisation is often suspected to be too low. The aim of this study was to describe the epidemiology of LLD use with special emphasis on the development of utilisation over a 6-year period in a Danish population. Methods: For all people who purchased LLDs from 1993 to 1998 in Funen County, all prescriptions for LLDs and co-medication with cardiovascular and antidiabetic drugs were retrieved from Odense University Pharmacoepidemiologic Database (OPED). Results: During the study period, LLD use increased nearly exponentially. In 1998, statins accounted for 95% of the total LLD consumption. The incidence increased markedly around the time of the publication of the Scandinavian Simvastatin Survival Study (4S). Only 3% of the statins were purchased without reimbursement. The female/male ratio was 0.69 and the median age was60 years. General practitioners issued 73% of the total number of LLD prescriptions, and 55% of the treatments were initiated in general practice. A larger fraction of females and elderly started treatment in general practice. About 40% of the treatments were hospital initiated, and about one-thirdwere followed up in general practice within the first year. Conclusions: Over the 6 years studied, utilisation of LLDs approached a level that may correspond to the current guideline recommendations. Compliance with guidelines should, however, be studied by following people with coronary heart disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 04:01:56