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Titolo:
Progress in the modeling of neurodegenerative diseases in transgenic mice
Autore:
Duff, K; Rao, MV;
Indirizzi:
Nathan S Kline Inst Psychiat Res, Orangeburg, NY 10962 USA Nathan S Kline Inst Psychiat Res Orangeburg NY USA 10962 rg, NY 10962 USA
Titolo Testata:
CURRENT OPINION IN NEUROLOGY
fascicolo: 4, volume: 14, anno: 2001,
pagine: 441 - 447
SICI:
1350-7540(200108)14:4<441:PITMON>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
AMYOTROPHIC-LATERAL-SCLEROSIS; CU/ZN SUPEROXIDE-DISMUTASE; MOTOR-NEURON DISEASE; GLIAL GLUTAMATE TRANSPORTER; AMYLOID PRECURSOR PROTEIN; ALZHEIMERS-DISEASE; MOUSE MODEL; AXONAL-TRANSPORT; TAU-PROTEIN; APOLIPOPROTEIN-E;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
75
Recensione:
Indirizzi per estratti:
Indirizzo: Duff, K Nathan S Kline Inst Psychiat Res, 140 Old Orangeburg Rd, Orangeburg, NY 10962 USA Nathan S Kline Inst Psychiat Res 140 Old Orangeburg Rd Orangeburg NY USA 10962
Citazione:
K. Duff e M.V. Rao, "Progress in the modeling of neurodegenerative diseases in transgenic mice", CURR OP NEU, 14(4), 2001, pp. 441-447

Abstract

Transgenic mouse models exist for the major neurodegenerative diseases, including Alzheimer's disease, tauopathy and amyotrophic lateral sclerosis. Although many of the mice do not completely replicate the human disease theyare intended to model, they have provided insight into the mechanisms thatunderlie disease etiology. In the case of the Alzheimer's disease and amyotrophic lateral sclerosis models, the mice have also provided a therapeutictesting ground for the testing of agents that have been shown to have considerable clinical promise. Curr Opin Neurol 14:441-447. (C) 2001 LippincottWilliams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 18:24:53