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Titolo:
Selective internal radiation therapy by yttrium-90 microspheres for hepatocellular carcinoma after renal transplantation
Autore:
Szeto, CC; Wong, TYH; Leung, CB; Leung, TWT; Wang, AYM; Lui, SF; Li, PKT;
Indirizzi:
Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut, Shatin, Hong Kong, Peoples R China Chinese Univ Hong Kong Shatin Hong Kong Peoples R China Peoples R China
Titolo Testata:
CLINICAL TRANSPLANTATION
fascicolo: 4, volume: 15, anno: 2001,
pagine: 284 - 288
SICI:
0902-0063(200108)15:4<284:SIRTBY>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
TC-99M MACROAGGREGATED ALBUMIN; PRIMARY LIVER-CANCER; Y-90 MICROSPHERES; HONG-KONG; PHASE-II; TRIAL;
Keywords:
hepatocellular carcinoma; kidney transplant; radiotherapy;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Szeto, CC Chinese Univ Hong Kong, Prince Wales Hosp, Dept Med & Therapeut,Shatin, Hong Kong, Peoples R China Chinese Univ Hong Kong Shatin Hong Kong Peoples R China China
Citazione:
C.C. Szeto et al., "Selective internal radiation therapy by yttrium-90 microspheres for hepatocellular carcinoma after renal transplantation", CLIN TRANSP, 15(4), 2001, pp. 284-288

Abstract

We report a HBsA-positive patient who developed hepatocellular carcinoma (HCC) 7 years after cadaveric kidney transplantation. The tumor was unresectable because of coexisting cirrhosis. Selective internal radiation (SIR) therapy, a novel therapy with the technique recently perfected, was used. Yttrium-90 microspheres were given via an angiographic catheter under fluoroscopy guidance. Serum alpha-fetal protein (AFP) was normalized within 2 wk. Afollow-up abdominal CT scan revealed significant necrosis of the tumor andcompensatory hypertrophy of non-diseased liver. The treatment was well tolerated except for transient liver function deterioration. The patient enjoyed 15 months of symptom-free survival before she died of liver failure. Practical aspects and potential applications of SIR therapy in this group of patients are discussed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/12/20 alle ore 22:24:13