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Titolo:
Diagnostic radiation and the risk of multiple myeloma (United States)
Autore:
Hatcher, JL; Baris, D; Olshan, AF; Inskip, PD; Savitz, DA; Swanson, GM; Pottern, LM; Greenberg, RS; Schwartz, AG; Schoenberg, JB; Brown, LM;
Indirizzi:
Univ N Carolina, Sch Publ Hlth, Dept Epidemiol, Chapel Hill, NC USA Univ NCarolina Chapel Hill NC USA , Dept Epidemiol, Chapel Hill, NC USA NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA NCI Bethesda MD USA 20892 Canc Epidemiol & Genet, Bethesda, MD 20892 USA Michigan Canc Fdn, Detroit, MI 48201 USA Michigan Canc Fdn Detroit MI USA48201 an Canc Fdn, Detroit, MI 48201 USA Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA Emory Univ Atlanta GA USA 30322 lins Sch Publ Hlth, Atlanta, GA 30322 USA New Jersey State Dept Hlth, Trenton, NJ 08625 USA New Jersey State Dept Hlth Trenton NJ USA 08625 th, Trenton, NJ 08625 USA Karmanos Canc Inst, Detroit, MI USA Karmanos Canc Inst Detroit MI USAKarmanos Canc Inst, Detroit, MI USA
Titolo Testata:
CANCER CAUSES & CONTROL
fascicolo: 8, volume: 12, anno: 2001,
pagine: 755 - 761
SICI:
0957-5243(200110)12:8<755:DRATRO>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Keywords:
case-control studies; ionizing radiation; multiple myeloma; X-rays;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
32
Recensione:
Indirizzi per estratti:
Indirizzo: Hatcher, JL 433 3rd St NE, Washington, DC 20002 USA 433 3rd St NE Washington DC USA 20002 ashington, DC 20002 USA
Citazione:
J.L. Hatcher et al., "Diagnostic radiation and the risk of multiple myeloma (United States)", CANC CAUSE, 12(8), 2001, pp. 755-761

Abstract

Objective: To evaluate the relationship between cumulative lifetime exposure to diagnostic radiation and the risk of multiple myeloma using data froma large, multi-center, population-based case-control study. Methods: Study subjects included a total of 540 cases with newly diagnosedmultiple myeloma and 1998 frequency-matched population controls living in three areas of the United States (Georgia, Michigan, New Jersey). Information on exposure to diagnostic X-rays was obtained by personal interview. Results: No association was found between case-control status and the total number of reported diagnostic X-rays of any type (odds ratio (OR) for 20 or more compared to less than 5 X-rays = 0.9, 95% confidence interval (95% CI) = 0.7-1.2). There was no evidence of an excess risk of multiple myelomaamong individuals who reported exposure to 10 or more diagnostic X-rays that impart a relatively high radiation dose to the bone marrow, as compared to individuals reporting no such exposures (OR 0.7, 95% CI 0.4-1.3). Conclusions: These data suggest that exposure to diagnostic X-rays has a negligible impact, if any, on risk of developing multiple myeloma.

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Documento generato il 03/06/20 alle ore 09:16:26