Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Fetal lung volume measurement by magnetic resonance imaging in congenital diaphragmatic hernia
Autore:
Mahieu-Caputo, D; Sonigo, P; Dommergues, M; Fournet, JC; Thalabard, JC; Abarca, C; Benachi, A; Brunelle, F; Dumez, Y;
Indirizzi:
Necker Hosp Sick Children, Paris, France Necker Hosp Sick Children ParisFrance osp Sick Children, Paris, France
Titolo Testata:
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
fascicolo: 8, volume: 108, anno: 2001,
pagine: 863 - 868
SICI:
1470-0328(200108)108:8<863:FLVMBM>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
IN-UTERO; 3-DIMENSIONAL ULTRASONOGRAPHY; ULTRASOUND DIAGNOSIS; PULMONARY HYPOPLASIA; PROGNOSTIC FACTORS; SURVIVAL; FETUSES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Mahieu-Caputo, D Maternite Hop Necker Enfants Malades, 149 Rue Sevres, Paris, France Maternite Hop Necker Enfants Malades 149 Rue Sevres Paris France
Citazione:
D. Mahieu-Caputo et al., "Fetal lung volume measurement by magnetic resonance imaging in congenital diaphragmatic hernia", BR J OBST G, 108(8), 2001, pp. 863-868

Abstract

Objective To study the potential for prenatal magnetic resonance imaging to predict pulmonary hypoplasia in congenital diaphragmatic hernia. Design Prospective observational study. Setting Tertiary care centre. Participants Thirteen cases of congenital diaphragmatic hernia (11 left, 2right) without associated anomalies and 74 controls. Methods Measurements by magnetic resonance imaging of fetal lung volume were achieved. In the control fetuses, a regression analysis was performed toassociate fetal lung volume with gestational age. This yielded a formula allowing calculation of the expected fetal lung volume as a function of gestational age. In the cases with congenital diaphragmatic hernia, the observed/expected fetal lung volume ratio was compared with perinatal outcome. Main outcome measures Neonatal mortality and pulmonary hypoplasia, which was defined as lung/body weight ratios less than 0.012. C,Results The expected fetal lung volume was derived from the following formula: Fetal lung volume (mL) exp (1.24722 + 0.08939 X gestational age in weeks). The observed/expected fetal lung volume ratio was significantly lower in congenital diaphragmatic hernia (median: 0.31, range: 0.06-0.63), than in controls (median: 0.99, range: 0.42-1.94). This ratio was significantly less in the infants with congenital diaphragmatic hernia who died (median: 0.26, range: 0.06-0.63) compared with those who survived (median: 0.46, range: 0.35-0.56). The observed: expected fetal lung volume ratio was significantly correlated with the postmortem lung: body weight ratio. Conclusion In isolated con-enital diaphragmatic hernia, fetal lung volume measurement by magnetic resonance C imaging is a potential predictor of pulmonary hypoplasia and postnatal outcome. Further studies are required C, toestablish the clinical value of macynetic resonance imaging for the prenatal assessment of fetal lungs.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/05/20 alle ore 14:51:18