Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A randomised double-blind placebo controlled trial of low molecular weightheparin as prophylaxis in preventing venous thrombolic events after caesarean section: a pilot study
Autore:
Burrows, RF; Gan, ET; Gallus, AS; Wallace, EM; Burrows, EA;
Indirizzi:
Monash Univ, Med Ctr, Dept Obstet & Gynaecol, Clayton, Vic 3168, AustraliaMonash Univ Clayton Vic Australia 3168 ecol, Clayton, Vic 3168, Australia Monash Univ, Dept Haematol, Clayton, Vic 3168, Australia Monash Univ Clayton Vic Australia 3168 atol, Clayton, Vic 3168, Australia Flinders Univ S Australia, Dept Haematol, Adelaide, SA 5001, Australia Flinders Univ S Australia Adelaide SA Australia 5001 , SA 5001, Australia
Titolo Testata:
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY
fascicolo: 8, volume: 108, anno: 2001,
pagine: 835 - 839
SICI:
1470-0328(200108)108:8<835:ARDPCT>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
DEEP-VEIN THROMBOSIS; ELECTIVE HIP-SURGERY; UNFRACTIONATED HEPARIN; PULMONARY-EMBOLISM; HIGH-RISK; THROMBOPROPHYLAXIS; PREGNANCIES; DIAGNOSIS; THROMBOEMBOLISM; EXPERIENCE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Burrows, RF Monash Univ, Med Ctr, Dept Obstet & Gynaecol, 246 Clayton Rd, Clayton, Vic3168, Australia Monash Univ 246 Clayton Rd Clayton Vic Australia 3168 ustralia
Citazione:
R.F. Burrows et al., "A randomised double-blind placebo controlled trial of low molecular weightheparin as prophylaxis in preventing venous thrombolic events after caesarean section: a pilot study", BR J OBST G, 108(8), 2001, pp. 835-839

Abstract

Objective To pilot a protocol for a national multicentre randomised trial in which a low molecular weight heparin will be compared with placebo for prevention of venous thrombotic events occurring within six weeks after caesarean section. Design Double-blind randomised controlled trial. Setting Tertiary care centre. Participants Seventy-six women having had a caesarean section, 37 in the control group and 39 in the Dalteparin group. Methods Consenting patients having had an emergency or elective caesarean section were commenced on study medication 6-24 hours post-operatively. Thestudy medication, dalteparin 2500iu or saline, was oriven subcutaneously once daily for four or five days post-operatively depending on the patient'slength of stay. Patients were reviewed in hospital for operative outcomes and contacted at two and six weeks post-operatively. Results Of the 141 women given information about the trial, 76 (54%) consented to participate. Follow up to six weeks was achieved in all women who were recruited. More women in the placebo arm had general anaesthesia, but otherwise the two groups had similar characteristics at randomisation. Therewas only one occurrence of a deep vein thrombosis during the study. This patient was in the treatment arm and the thrombosis occurred between two andsix weeks post-operatively. All other outcomes were similar in the two groups. Conclusion Our experience of a 26% recruitment rate, the thrombosis rate of 1.3% (95% CI 0.03-7.1%) and the contactability of all participants two and six weeks post-operatively, indicates that this study is feasible.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 00:44:42