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Titolo:
Inflammatory pseudotumor of the submandibular gland - Report of a case presenting with autoimmune disease-like clinical manifestations
Autore:
Kojima, M; Nakamura, S; Itoh, H; Suchi, T; Masawa, N;
Indirizzi:
Dokkyo Univ, Sch Med, Dept Pathol, Mibu, Tochigi 3210923, Japan Dokkyo Univ Mibu Tochigi Japan 3210923 thol, Mibu, Tochigi 3210923, Japan Aichi Canc Ctr Hosp, Dept Pathol & Genet, Nagoya, Aichi 464, Japan Aichi Canc Ctr Hosp Nagoya Aichi Japan 464 enet, Nagoya, Aichi 464, Japan Maebashi Red Cross Hosp, Dept Pathol, Maebashi, Gumma, Japan Maebashi Red Cross Hosp Maebashi Gumma Japan hol, Maebashi, Gumma, Japan Maebashi Red Cross Hosp, Clin Labs, Maebashi, Gumma, Japan Maebashi Red Cross Hosp Maebashi Gumma Japan abs, Maebashi, Gumma, Japan
Titolo Testata:
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
fascicolo: 8, volume: 125, anno: 2001,
pagine: 1095 - 1097
SICI:
0003-9985(200108)125:8<1095:IPOTSG>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA-CELL GRANULOMAS; EPSTEIN-BARR-VIRUS; MYOEPITHELIAL SIALADENITIS; SALIVARY-GLANDS; LYMPHOMA; MONOCLONALITY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Kojima, M Dokkyo Univ, Sch Med, Dept Pathol, Mibu, Tochigi 3210923, Japan Dokkyo Univ Mibu Tochigi Japan 3210923 , Tochigi 3210923, Japan
Citazione:
M. Kojima et al., "Inflammatory pseudotumor of the submandibular gland - Report of a case presenting with autoimmune disease-like clinical manifestations", ARCH PATH L, 125(8), 2001, pp. 1095-1097

Abstract

We report a rare case of inflammatory pseudotumor arising in the submandibular gland, which presented with autoimmune disease-like clinical manifestations. A 70-year-old Japanese man developed masses in both submandibular regions. Laboratory tests revealed polyclonal hypergammaglobulinemia, high titers of antinuclear antibody, and a positive thyroid test. Histologically, the lesion was composed of multiple nodules separated by thick fibrous bands and contained a few atrophic lymphoid follicles and residual ductal structures. At higher magnification, the nodules contained numerous mature plasma cells mixed with myofibroblasts, lymphocytes, and histiocytes. Occasionally, the myofibroblasts were arranged in poorly formed fascicles and in a storiform pattern. Polymerase chain reaction analysis failed to demonstrated the rearrangement of the immunoglobulin heavy-chain gene. The patient was free of disease after 72 months follow-up. Marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type arising from salivary glands occasionally showed prominent plasma cell differentiation. The present caseindicates that inflammatory pseudotumor should be added to the list of different diagnoses for mucosa-associated lymphoid tissue-type lymphoma of thesalivary glands.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 01:05:01