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Titolo:
Case-control studies on host factors in severe malaria
Autore:
Nacher, M; Singhasivanon, P; Gay, F; Silachamroon, U; Looareesuwan, S;
Indirizzi:
Univ Paris 06, INSERM, U511, Unite Immunobiol Cellulaire & Mol Infect Parasita, F-75634 Paris 13, France Univ Paris 06 Paris France 13 Infect Parasita, F-75634 Paris 13, France Mahidol Univ, Fac Trop Med, Hosp Trop Dis, Bangkok 10400, Thailand MahidolUniv Bangkok Thailand 10400 sp Trop Dis, Bangkok 10400, Thailand
Titolo Testata:
TRENDS IN PARASITOLOGY
fascicolo: 6, volume: 17, anno: 2001,
pagine: 253 - 254
SICI:
1471-4922(200106)17:6<253:CSOHFI>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Soggetto:
FALCIPARUM-MALARIA; CEREBRAL MALARIA; GAMBIAN CHILDREN; RISK-FACTORS; DISEASE;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Nacher, M Univ Paris 06, INSERM, U511, Unite Immunobiol Cellulaire & Mol Infect Parasita, 91 Blvd Hop, F-75634 Paris 13, France Univ Paris 06 91 BlvdHop Paris France 13 5634 Paris 13, France
Citazione:
M. Nacher et al., "Case-control studies on host factors in severe malaria", TRENDS PARA, 17(6), 2001, pp. 253-254

Abstract

Although molecular biology has illustrated the phenotypic heterogeneity ofPlasmodium falciparum, there are still no specific markers of virulence. As parasite virulence is an important determinant of severe malaria, the choice of comparison groups in the study of host factors influencing severity is a delicate issue, Ignoring parasite factors in the selection of controlspotentially leads to biased comparisons between a majority of cases with virulent parasites and a majority of controls with non-virulent parasites. This article discusses how to avoid this virulence bias in the absence of specific markers of virulence.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:18:19