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Titolo:
Red blood cell transfusion strategies
Autore:
Blajchman, MA; Hebert, PC;
Indirizzi:
McMaster Univ, Dept Pathol & Mol Med, Hamilton, ON L8N 3Z5, Canada McMaster Univ Hamilton ON Canada L8N 3Z5 ed, Hamilton, ON L8N 3Z5, Canada Univ Ottawa, Dept Med & Clin Epidemiol, Ottawa, ON K1H 8L6, Canada Univ Ottawa Ottawa ON Canada K1H 8L6 pidemiol, Ottawa, ON K1H 8L6, Canada
Titolo Testata:
TRANSFUSION CLINIQUE ET BIOLOGIQUE
fascicolo: 3, volume: 8, anno: 2001,
pagine: 207 - 210
SICI:
1246-7820(200106)8:3<207:RBCTS>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
ARTERY BYPASS-SURGERY; CARDIAC-SURGERY; CLINICAL-TRIAL; MULTICENTER; MORTALITY; CARE;
Keywords:
anemia; oxygen delivery; RBC transfusion; transfusion practice; transfusion reaction; transfusion trigger;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Blajchman, MA McMaster Univ, Dept Pathol & Mol Med, 1200 Main St W,HSC 2N34, Hamilton, ON L8N 3Z5, Canada McMaster Univ 1200 Main St W,HSC 2N34 Hamilton ON Canada L8N 3Z5
Citazione:
M.A. Blajchman e P.C. Hebert, "Red blood cell transfusion strategies", TRANSF CL B, 8(3), 2001, pp. 207-210

Abstract

Although the hemoglobin level of 100 g/L has been used for many years as the allogeneic red blood cell (RBC) transfusion trigger, current evidence indicates that for most patients a more restrictive transfusion strategy is at least as effective as and possibly superior to a liberal transfusion strategy. Moreover, the available data indicate that the use of smaller volumesof allogeneic RBCs may be associated with decreased risk of morbidity and mortality. Thus several recent studies indicate that the use of more restrictive triggers than 100 g/L does not appear to adversely affect patient outcomes. Indeed, the majority of recently published RBC transfusion guidelines recommend a more conservative and cautious approach to allogeneic RBC transfusion practice, primarily to reduce the risk of transfusion-related adverse effects. However, the available transfusion trigger studies do not provide sufficient data to allow the claim that the improved outcomes observed are the sole result of the transfusion strategy used. It is possible that the results are the consequence of effects yet to be defined clearly. Additional studies will be necessary to determine the effects of RBC storage timeand the presence of allogeneic leukocytes in allogeneic RBC transfusion practice. Nonetheless, the available data, together with detailed informationabout alternatives to blood product transfusions, will enable physicians to improve outcomes in transfused patients. (C) 2001 Editions scientifiques et medicales Elsevier SAS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 10:12:00