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Titolo:
Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality
Autore:
Wong, TY; Klein, R; Klein, BEK; Tielsch, JM; Hubbard, L; Nieto, FJ;
Indirizzi:
Univ Wisconsin, Dept Ophthalmol & Visual Sci, Madison, WI 53705 USA Univ Wisconsin Madison WI USA 53705 l & Visual Sci, Madison, WI 53705 USA Natl Univ Singapore, Dept Ophthalmol, Singapore 0511, Singapore Natl Univ Singapore Singapore Singapore 0511 , Singapore 0511, Singapore Natl Univ Singapore, Singapore Natl Eye Ctr, Singapore 0511, Singapore Natl Univ Singapore Singapore Singapore 0511 , Singapore 0511, Singapore Johns Hopkins Univ, Sch Publ Hlth, Dept Int Hlth, Baltimore, MD USA Johns Hopkins Univ Baltimore MD USA th, Dept Int Hlth, Baltimore, MD USA Johns Hopkins Univ, Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA JohnsHopkins Univ Baltimore MD USA h, Dept Epidemiol, Baltimore, MD USA
Titolo Testata:
SURVEY OF OPHTHALMOLOGY
fascicolo: 1, volume: 46, anno: 2001,
pagine: 59 - 80
SICI:
0039-6257(200107/08)46:1<59:RMAATR>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY HEART-DISEASE; LEFT-VENTRICULAR HYPERTROPHY; VON-WILLEBRAND-FACTOR; MALIGNANT ARTERIAL-HYPERTENSION; JAPANESE PROVINCIAL CITY; VESSEL DIAMETER CHANGES; TARGET-ORGAN DAMAGE; RISK-FACTORS; DIABETIC-RETINOPATHY; BLOOD-PRESSURE;
Keywords:
arteriosclerosis; arteriovenous nicking; atherosclerosis; cardiovascular disease; hypertension; ischemic heart disease; retinal arteriolar narrowing; retinal arteriovenous ratio; retinal microvascular abnormalities; retinal photographic grading; retinopathy; stroke;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
221
Recensione:
Indirizzi per estratti:
Indirizzo: Wong, TY Univ Wisconsin, Dept Ophthalmol & Visual Sci, 610 N Walnut St,460WARF, Madison, WI 53705 USA Univ Wisconsin 610 N Walnut St,460 WARF Madison WI USA 53705 USA
Citazione:
T.Y. Wong et al., "Retinal microvascular abnormalities and their relationship with hypertension, cardiovascular disease, and mortality", SURV OPHTHA, 46(1), 2001, pp. 59-80

Abstract

Retinal microvascular abnormalities, such as generalized and focal arteriolar narrowing, arteriovenous nicking and retinopathy, reflect cumulative vascular damage from hypertension, aging, and other processes. Epidemiological studies indicate that these abnormalities can be observed in 2-5% of the nondiabetic general population and are strongly and consistently associatedwith elevated blood pressure. Generalized arteriolar narrowing and arteriovenous nicking also appear to be irreversible long-term markers of hypertension, related not only to current but past blood pressure levels as well. There are data supporting an association between retinal microvascular abnormalities and stroke, but there is no convincing evidence of an independent or direct association with atherosclerosis, ischemic heart disease, or cardiovascular mortality. New computer-related imaging methods are currently being developed to detect the presence and severity of retinal arteriolar narrowing and other microvascular characteristics. When reliably quantified, retinal microvascular abnormalities may be useful as risk indicators for cerebrovascular diseases. (Surv Ophthalmol 46:59-80, 2001. (C) 2001 by Elsevier Science Inc. All rights reserved.).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 02:25:17