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Titolo:
Psychosis treatment prior to psychosis onset: ethical issues
Autore:
McGlashan, TH;
Indirizzi:
Yale Univ, Sch Med, Dept Psychiat, New Haven, CT 06520 USA Yale Univ New Haven CT USA 06520 , Dept Psychiat, New Haven, CT 06520 USA
Titolo Testata:
SCHIZOPHRENIA RESEARCH
fascicolo: 1, volume: 51, anno: 2001,
pagine: 47 - 54
SICI:
0920-9964(20010801)51:1<47:PTPTPO>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLIND OLANZAPINE TRIAL; TARDIVE-DYSKINESIA; CLINICAL RESEARCH; LONG-TERM; SCHIZOPHRENIA; HALOPERIDOL; INTERVENTION; EQUIPOISE;
Keywords:
antipsychotic treatments; psychosis; schizophrenia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: McGlashan, TH Yale Univ, Sch Med, Dept Psychiat, POB 208098, New Haven, CT06520 USA Yale Univ POB 208098 New Haven CT USA 06520 en, CT 06520 USA
Citazione:
T.H. McGlashan, "Psychosis treatment prior to psychosis onset: ethical issues", SCHIZOPHR R, 51(1), 2001, pp. 47-54

Abstract

Clinical trials have begun of antipsychotic treatments in persons who are prodromally symptomatic and at high risk for schizophrenia but who have notyet become psychotic. The ethical issues connected with intervening prior to making a diagnosis of psychosis are detailed. Compelling but tentative evidence suggests that early treatment may improve course and prognosis, andthis has initiated a paradigm shift in thinking about the risks and benefits of early intervention. The nature of this evidence, its implications, its shortcomings, and its effect upon the ethics of treating schizophrenia are elaborated and discussed. It is concluded that clinical psychiatry is currently in a state of "equipoise" or genuine uncertainty about the comparative merits of early treatment, a state which endorses early intervention research, including intervention in the prodromal phase. (C) 2001 Elsevier Science B.V. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 23/01/20 alle ore 03:33:11