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Titolo:
Bronchial arterial devascularization. An experimental study in pigs
Autore:
Gade, J; Qvortrup, K; Andersen, CB; Thorsen, S; Svendsen, UG; Olsen, PS;
Indirizzi:
Copenhagen Univ Hosp, Rigshosp, RT 2152, Dept Cardiothorac Surg, Copenhagen, Denmark Copenhagen Univ Hosp Copenhagen Denmark horac Surg, Copenhagen, Denmark Univ Copenhagen, Panum Inst, Dept Med Anat, Sect B, DK-1168 Copenhagen, Denmark Univ Copenhagen Copenhagen Denmark DK-1168 , DK-1168 Copenhagen, Denmark Copenhagen Univ Hosp, Rigshosp, Dept Pathol, Copenhagen, Denmark Copenhagen Univ Hosp Copenhagen Denmark ept Pathol, Copenhagen, Denmark Univ Copenhagen, Panum Inst, Dept Expt Med, DK-1168 Copenhagen, Denmark Univ Copenhagen Copenhagen Denmark DK-1168 , DK-1168 Copenhagen, Denmark Copenhagen Univ Hosp, Rigshosp, Dept Med B, Copenhagen, Denmark CopenhagenUniv Hosp Copenhagen Denmark Dept Med B, Copenhagen, Denmark
Titolo Testata:
SCANDINAVIAN CARDIOVASCULAR JOURNAL
fascicolo: 3, volume: 35, anno: 2001,
pagine: 212 - 220
SICI:
1401-7431(200107)35:3<212:BADAES>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
DOUBLE-LUNG TRANSPLANTATION; LASER DOPPLER FLOWMETRY; SYSTEMIC BLOOD-FLOW; REVASCULARIZATION; CIRCULATION; PULMONARY; MODEL;
Keywords:
bronchi; devascularization; ischaemia; morphology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Gade, J Rigshosp, RT 2152, Dept Thorac Surg, Blegdamsvej 9, DK-2100 Copenhagen O, Denmark Rigshosp Blegdamsvej 9 Copenhagen Denmark O Copenhagen O, Denmark
Citazione:
J. Gade et al., "Bronchial arterial devascularization. An experimental study in pigs", SC CARDIOVA, 35(3), 2001, pp. 212-220

Abstract

Objective-The lungs have dual blood supply: The bronchial and the pulmonary circulation. The importance of bronchial circulation is disputed. The purpose of this study was to establish an experimental model to examine the importance of the bronchial artery. Design-Comparative porcine experimental study. The surgical technique was evaluated in group A (n = 9). Group B (n = 8) underwent left bronchial arterial devascularization. In group C (n = 9) the left principal bronchus was devascularized, transsected, and reanastomosed. In groups B and C bronchialmucosal blood flow was studied with laser-Doppler velocimetry. Devascularization was controlled by angiography at section, and specimens were examined with conventional histology and scanning electron microscopy. The right bronchus served as control. Results-In group B devascularization caused considerable, yet insignificant reduction in bronchial mucosal blood flow index (p = 0.1282) postoperatively, and after 1 week (p = 0.0678), insignificant histologic (p > 0.2) changes, and no scanning electron microscopy differences. In group C devascularization with bronchial transsection caused significant reduction in mucosalblood flow index (p = 0.0277) postoperatively and after 1 week (p = 0.0277), significant histologic changes (p = 0.0277), and insignificant (p = 0.069) changes in scanning electron microscopy. Conclusion-Bronchial arterial devascularization with transsection caused significant physiologic and morphologic changes, and a model with bronchial devascularization should include transsection.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/11/20 alle ore 18:50:29