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Titolo:
Surveillance and prognosis of stage Ta superficial bladder cancers. A homogeneous series of 138 cases followed for 1 to 18 years
Autore:
Lachand, AT; Texier, J; Texier, P;
Indirizzi:
Clin Sarrette, Paris, France Clin Sarrette Paris FranceClin Sarrette, Paris, France
Titolo Testata:
PROGRES EN UROLOGIE
fascicolo: 3, volume: 11, anno: 2001,
pagine: 466 - 471
SICI:
1166-7087(200106)11:3<466:SAPOST>2.0.ZU;2-R
Fonte:
ISI
Lingua:
FRE
Soggetto:
PROGRESSION; RECURRENCE; TUMOR;
Keywords:
superficial bladder cancer; prognosis; risk factors;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
13
Recensione:
Indirizzi per estratti:
Indirizzo: Lachand, AT 23 Rue Pere Corentin, F-75014 Paris, France 23 Rue Pere Corentin Paris France F-75014 5014 Paris, France
Citazione:
A.T. Lachand et al., "Surveillance and prognosis of stage Ta superficial bladder cancers. A homogeneous series of 138 cases followed for 1 to 18 years", PROG UROL, 11(3), 2001, pp. 466-471

Abstract

Objective: To identify prognostic factors (risk of recurrence and risk of progression) and define the rules for the surveillance of stage Ta superficial bladder cancers, based on the follow-up of a homogeneous patient series. Material and Method: 138 Ta bladder cancers were recruited front 1975 to 1995 and regularly followed by the saute urologist. The follow-up was 1 to 18 years with a mean of 66 months and a median of 60 months. Results: 30% of patients developed no recurrence (mean followup: 52 months). 70% developed one or several recurrences (mean follow-up: 80 months): 46% of Ta recurrences without progression and 24% of T greater than or equal to 1, with 10% of T > 1 recurrencesd.13/138 patients died from bladder cancer including 11 patients in less than 10 years. The risk of recurrence and the risk of progression were significantly correlated with:the macroscopic appearance of the cancer: size, number and extent of implantations, sessile or pedunculated nature,its site: slightly more serious on the fixed part of the organ,its clinical course assessed over the first 12 months: in patients withoutrecurrence at 12 months:the risk of recurrence decreased from 70% to 35%the risk of deterioration decreased from 24% to 10%. However this risk persisted in the long term: after more than 5 years without recurrence, 2 patients developed fatal recurrences, 11 and 15 years after the initial treatment. Conclusion: Although superficial, Ta bladder cancers are serious cancers. The risk of recurrence and progression justify close surveillance in the year following diagnosis. Subsequently, the frequency of follow-up can be adapted to the specific course of each case, but, regardless of these modalities, long-term (indefinite?) surveillance is recommended.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 01/04/20 alle ore 11:47:10