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Titolo:
Collaborative study on drug use in pregnancy: the results of the follow-up10 years after (Novi Sad Centre)
Autore:
Sabo, A; Stanulovic, M; Jakovljevic, V; Grujic, Z;
Indirizzi:
Fac Med Novi Sad, Dept Pharmacol Toxicol & Clin Pharmacol, PB 380, YU-21001 Novi Sad, Yugoslavia Fac Med Novi Sad Novi Sad Yugoslavia YU-21001 21001 Novi Sad, Yugoslavia Dept Obstet & Gynecol, Novi Sad, Yugoslavia Dept Obstet & Gynecol Novi Sad Yugoslavia Gynecol, Novi Sad, Yugoslavia
Titolo Testata:
PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
fascicolo: 3, volume: 10, anno: 2001,
pagine: 229 - 235
SICI:
1053-8569(200105)10:3<229:CSODUI>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Keywords:
drug use; pregnancy; puerperium; lactation; pharmacoepidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Sabo, A Fac Med Novi Sad, Dept Pharmacol Toxicol & Clin Pharmacol, PB 380,Hajduk Veljka 3, YU-21001 Novi Sad, Yugoslavia Fac Med Novi Sad Hajduk Veljka 3 Novi Sad Yugoslavia YU-21001 via
Citazione:
A. Sabo et al., "Collaborative study on drug use in pregnancy: the results of the follow-up10 years after (Novi Sad Centre)", PHARMA D S, 10(3), 2001, pp. 229-235

Abstract

An international multicenter study entitled Collaborative Study on Drug Use in Pregnancy (DUP) was initiated in 1987 by the Mario Negri Institute (Milano) and co-sponsored by the WHO Regional Office for Europe (Copenhagen). The study covered the use of medicines during pregnancy, labour and postpartum period. The Novi Sad centre contributed with 296 questionnaires. The aim of the study was to evaluate the pharmacotherapy by means of comparison, to identify problems in a particular settings and to plan actions toward improvement. The prescribing of some medicines in the Novi Sad center was found to be at the extreme, being among the lowest in the use of iron preparations during pregnancy and among the highest in the use of ergot alkaloids in the postpartum period. Educational efforts have been made to change this practice after the conclusion of the study in 1989. Ten years later, in 1999, the same questionnaire was applied to 100 women in the postpartum periodin the same nursery, the Department of Obstetrics and Gynecology in Novi Sad. The results have shown a distinct improvement with the increase of ironprescribing during pregnancy and almost complete abandonment of postpartumuse of ergot alkaloids. In the second study period some other inconsistencies with accepted therapeutical principles were identified. For example, although the use of analgesics fell from 22.3 to 8%, the selection changed towards the high use of metamizole (noraminophenazone) and no use of paracetamol (acetaminophen). It was concluded that international pharmacoepidemiological studies such as DUP, could substantially contribute to the improvement of pharmacotherapy if followed by appropriate actions in changing the prescribing behaviour of the physicians and information directed to the targetpopulation. Copyright (C) 2001 John Wiley & Sons, Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 24/01/20 alle ore 12:33:48