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Titolo:
Beyond informed consent: The ethical design of pain research
Autore:
Casarett, DJ; Karlawish, J;
Indirizzi:
Univ Penn, Philadelphia VA Med Ctr, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 A Med Ctr, Philadelphia, PA 19104 USA Univ Penn, Inst Aging, Div Geriatr, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 v Geriatr, Philadelphia, PA 19104 USA Univ Penn, Ctr Bioeth, Philadelphia, PA 19104 USA Univ Penn Philadelphia PA USA 19104 tr Bioeth, Philadelphia, PA 19104 USA
Titolo Testata:
PAIN MEDICINE
fascicolo: 2, volume: 2, anno: 2001,
pagine: 138 - 146
SICI:
1526-2375(200106)2:2<138:BICTED>2.0.ZU;2-L
Fonte:
ISI
Lingua:
ENG
Soggetto:
CONTROLLED-RELEASE OXYCODONE; QUALITY-OF-LIFE; CANCER-PATIENTS; CLINICAL RESEARCH; ORAL MORPHINE; DOUBLE-BLIND; TRANSDERMAL FENTANYL; SATISFACTION; TRIALS; MANAGEMENT;
Keywords:
pain; ethics; research ethics; informed consent;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
61
Recensione:
Indirizzi per estratti:
Indirizzo: Casarett, DJ Univ Penn, Philadelphia VA Med Ctr, 3615 Chestnut St, Philadelphia, PA 19104 USA Univ Penn 3615 Chestnut St Philadelphia PA USA 19104 9104 USA
Citazione:
D.J. Casarett e J. Karlawish, "Beyond informed consent: The ethical design of pain research", PAIN MED, 2(2), 2001, pp. 138-146

Abstract

In the wake of the rapid development of medical research over the past 50 years, investigators, clinicians, and ethicists have raised numerous concerns about the ethical conduct of research. Perhaps the single most importantprotective mechanism to emerge from the fray has been flue requirement of informed consent. Certainly it has the longest history. however, even th ugh informed consent has become the most widely recognized mechanism of protecting human subjects in research, there are limits to what the informed consent process can accomplish. Another, anti more tar-reaching, way to protect human subjects involved in research is to ensure that the study design isas consistent as possible with patients' preferences and goals. That is, pain investigators have a significant opportunity to improve the ethical rigor of their work by designing a study that offers a subject what is a reasonable balance of risks and benefits. This article suggests some specific: ways in which investigators may design research that is more consistent withpatient preferences. We describe several aspects of the ethical design of clinical pain research that appear to be important to patients, including the potential benefits for subjects, the benefits for future patients, the risks anti burdens of research participation, and the voluntariness of a subject's choice whether to enroll. We conclude fy discussing ways in which the ethical design of research might make the informed consent process more robust.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:52:15