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Titolo:
Carcinoma of the hard palate treated with radiotherapy: a retrospective review of 31 cases
Autore:
Yorozu, A; Sykes, AJ; Slevin, NJ;
Indirizzi:
Christie Hosp, Manchester M20 4BX, Lancs, England Christie Hosp Manchester Lancs England M20 4BX er M20 4BX, Lancs, England
Titolo Testata:
ORAL ONCOLOGY
fascicolo: 6, volume: 37, anno: 2001,
pagine: 493 - 497
SICI:
1368-8375(200109)37:6<493:COTHPT>2.0.ZU;2-V
Fonte:
ISI
Lingua:
ENG
Soggetto:
ADENOID CYSTIC CARCINOMA; HEAD; NECK; MANAGEMENT; RADIATION;
Keywords:
carcinoma; hard palate; radiotherapy; squamous cell carcinoma; adenoid cystic carcinoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Sykes, AJ Christie Hosp, Wilmslow Rd, Manchester M20 4BX, Lancs, England Christie Hosp Wilmslow Rd Manchester Lancs England M20 4BX gland
Citazione:
A. Yorozu et al., "Carcinoma of the hard palate treated with radiotherapy: a retrospective review of 31 cases", ORAL ONCOL, 37(6), 2001, pp. 493-497

Abstract

There are few studies reporting the results of radical radiotherapy for carcinoma of the hard palate. We have examined our results of patients treated within a single institution, and assessed survival, local control and morbidity. A retrospective analysis was made on 31 patients with hard palate carcinoma treated with external beam radiotherapy at the Christie Hospital between 1990 and 1997. Twenty-six patients received radiotherapy alone and five were treated for post-operative positive surgical margins. The 5-year actuarial survival rate was 55%. The actuarial 5-year local control rate was53%, rising up to 69% after salvage surgery. Survival was 48% for squamouscell carcinomas and 63% for salivary gland carcinomas, the difference was not significant. The only significant predictor of local control was T-stage, with 80% 5-year local control of T1-2 lesions and 24% control of T3-4 lesions. N-stage was the only significant factor predicting for survival. Radiation necrosis occurred in one patient. Radical radiotherapy for carcinomaof the hard palate is safe and well tolerated. It is an effective treatment for both squamous cell carcinoma and salivary gland carcinoma. (C) 2001 Elsevier Science Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 19:35:00