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Titolo:
Alteration of rCBF in Alzheimer's disease patients with delusions of theft
Autore:
Fukuhara, R; Ikeda, M; Nebu, A; Kikuchi, T; Maki, N; Hokoishi, K; Shigenobu, K; Komori, K; Tanabe, H;
Indirizzi:
Ehime Univ, Sch Med, Dept Neuropsychiat, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 Shigenobu, Ehime 7910295, Japan Ehime Univ, Sch Med, Dept Radiol, Shigenobu, Ehime 7910295, Japan Ehime Univ Shigenobu Ehime Japan 7910295 Shigenobu, Ehime 7910295, Japan
Titolo Testata:
NEUROREPORT
fascicolo: 11, volume: 12, anno: 2001,
pagine: 2473 - 2476
SICI:
0959-4965(20010808)12:11<2473:AORIAD>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPECT; PSYCHOSIS;
Keywords:
age, sex, cognitive impairment-matched case-controlled study; Alzheimer's disease; Alzheimer's disease Assessment Scale cognitive; subscale (ADAScog.); delusions of theft; Neuropsychiatric Inventory (NPI); Statistical Parametric Mapping (SPM); Tc-99m-HMPAO SPECT;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
23
Recensione:
Indirizzi per estratti:
Indirizzo: Ikeda, M Univ Cambridge, Addenbrookes Hosp, Neurol Unit, Box 165,Hills Rd,Cambridge CB2 2QQ, England Univ Cambridge Box 165,Hills Rd Cambridge England CB2 2QQ ngland
Citazione:
R. Fukuhara et al., "Alteration of rCBF in Alzheimer's disease patients with delusions of theft", NEUROREPORT, 12(11), 2001, pp. 2473-2476

Abstract

We investigated the neural substrate of the delusion of theft in patients with Alzheimer's disease (AD). Nine AD patients with only one type of delusion (delusions of theft) and nine age, cognitive function-matched AD patients without any type of delusions were selected from 334 consecutive outpatients of Ehime University Hospital. All subjects underwent Tc-99m-HMPAO SPECT scanning, and SPECT images were analyzed by Statistical Parametric Mapping (SPM). AD patients with delusions of theft showed significant hypoperfusion in the right medial posterior parietal region compared to patients without delusions. Our data suggest that attention impairment or lack of awareness of illness caused by right parietal dysfunction might play a role in producing the delusion of theft. NeuroReport 12:2473-2476 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 17/09/19 alle ore 22:54:04