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Titolo:
Magnetisation transfer measurements of the subcortical grey and white matter in Parkinson's disease with and without dementia and in progressive supranuclear palsy
Autore:
Hanyu, H; Asano, T; Sakurai, H; Takasaki, M; Shindo, H; Abe, K;
Indirizzi:
Tokyo Med Univ, Dept Geriatr Med, Shinjuku Ku, Tokyo 1600023, Japan Tokyo Med Univ Tokyo Japan 1600023 ed, Shinjuku Ku, Tokyo 1600023, Japan Tokyo Med Univ, Dept Radiol, Shinjuku Ku, Tokyo 1600023, Japan Tokyo Med Univ Tokyo Japan 1600023 ol, Shinjuku Ku, Tokyo 1600023, Japan
Titolo Testata:
NEURORADIOLOGY
fascicolo: 7, volume: 43, anno: 2001,
pagine: 542 - 546
SICI:
0028-3940(200107)43:7<542:MTMOTS>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
RICHARDSON-OLSZEWSKI-SYNDROME; MAGNETIZATION-TRANSFER MEASUREMENTS; MULTIPLE SYSTEM ATROPHY; ALZHEIMERS-DISEASE; RESONANCE SPECTROSCOPY; INTERNATIONAL WORKSHOP; VASCULAR DEMENTIA; TRANSFER CONTRAST; TRANSFER RATIO; DIAGNOSIS;
Keywords:
Parkinson's disease; dementia; progressive supranuclear palsy; magnetisation transfer ratio;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
33
Recensione:
Indirizzi per estratti:
Indirizzo: Hanyu, H Tokyo Med Univ, Dept Geriatr Med, Shinjuku Ku, 6-7-1 Nishishinjuku, Tokyo 1600023, Japan Tokyo Med Univ 6-7-1 Nishishinjuku Tokyo Japan 1600023 23, Japan
Citazione:
H. Hanyu et al., "Magnetisation transfer measurements of the subcortical grey and white matter in Parkinson's disease with and without dementia and in progressive supranuclear palsy", NEURORADIOL, 43(7), 2001, pp. 542-546

Abstract

We measured the magnetisation transfer ratio (MTR) in the subcortical greyand white matter of 11 patients with idiopathic Parkinson's disease (PD) without dementia, six with PD with dementia (PDD), six with progressive supranuclear palsy (PSP), and 12 elderly control subjects to assess regional differences in structural brain damage. There were no significant differencesin MTR in any region between PD and controls. However, patients with PDD had significantly lower MTR in the subcortical white matter, including the frontal white matter and the genu of the corpus callosum than the controls, whereas PSP had significantly lower MTR in the subcortical grey matter, including the putamen, globus pallidus and thalamus, in addition to the subcortical white matter. This suggests that regional patterns of structural brain damage can be detected using the magnetisation transfer technique. Measurement of MTR in the subcortical. grey and white matter may be useful in differential diagnosis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 09:46:21