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Titolo:
Functional MRI in patients with band heterotopia
Autore:
Spreer, J; Martin, P; Greenlee, MW; Wohlfarth, R; Hammen, A; Arnold, SM; Schumacher, M;
Indirizzi:
Univ Freiburg, Dept Neuroradiol, Freiburg, Germany Univ Freiburg Freiburg Germany urg, Dept Neuroradiol, Freiburg, Germany Epilepsiezentrum Kehl Kork, Freiburg, Germany Epilepsiezentrum Kehl Kork Freiburg Germany ehl Kork, Freiburg, Germany Univ Freiburg, Neurol Clin, Freiburg, Germany Univ Freiburg Freiburg Germany Freiburg, Neurol Clin, Freiburg, Germany
Titolo Testata:
NEUROIMAGE
fascicolo: 2, volume: 14, anno: 2001,
pagine: 357 - 365
SICI:
1053-8119(200108)14:2<357:FMIPWB>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSITRON-EMISSION-TOMOGRAPHY; SUBCORTICAL LAMINAR HETEROTOPIA; RECEPTIVE-FIELD PROPERTIES; DOUBLE CORTEX SYNDROME; CORTICAL-NEURONS; DENTATE GYRUS; REELER MOUSE; HMPAO-SPECT; FDG-PET; MIGRATION;
Keywords:
fMRI; double cortex; laminar heterotopia;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Spreer, J Univ Freiburg, Dept Neuroradiol, Freiburg, Germany Univ Freiburg Freiburg Germany Neuroradiol, Freiburg, Germany
Citazione:
J. Spreer et al., "Functional MRI in patients with band heterotopia", NEUROIMAGE, 14(2), 2001, pp. 357-365

Abstract

Functional activation associated with a motor task (fist movements) was studied in three patients with band heterotopias by fMRI. In two patients, additional visual fMRI studies were performed using a flickering checkerboardstimulus. In all patients activation of the outer cortex and of the inner neuronal band could be found during performance of the motor task. Visual stimulation elicited a normal activation pattern wit out activation of the ectopic neuronal layer in one patient; in another patient activation extended toward the ventricular wall, i.e., along the route of embryonic neuronal migration. The potential participation of ectopic neuronal tissue in physiologic cerebral functions is of clinical impact in patients with neuronal heterotopias suffering from medically intractable seizures prior to epilepsy surgery. (C) 2001 Academic Press.

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Documento generato il 17/09/19 alle ore 18:47:04