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Titolo:
Expression analysis of the histamine H-3 receptor in developing rat tissues
Autore:
Heron, A; Rouleau, A; Cochois, V; Pillot, C; Schwartz, JC; Arrang, JM;
Indirizzi:
Fac sci Pharmaceut & Biol, Physiol Lab, F-75006 Paris, France Fac sci Pharmaceut & Biol Paris France F-75006 ab, F-75006 Paris, France INSERM, Unite Neurobiol & Pharmacol Mol U109, Ctr Paul Broca, F-75014 Paris, France INSERM Paris France F-75014 U109, Ctr Paul Broca, F-75014 Paris, France
Titolo Testata:
MECHANISMS OF DEVELOPMENT
fascicolo: 1-2, volume: 105, anno: 2001,
pagine: 167 - 173
SICI:
0925-4773(200107)105:1-2<167:EAOTHH>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
HISTIDINE-DECARBOXYLASE; IMMUNOREACTIVE NEURONS; BRAIN; CLONING; PROLIFERATION; SECRETION; RELEASE; AGONIST; CELLS;
Keywords:
histamine; H-3 receptor; L-histidine decarboxylase; rat; in situ hybridization; reverse transcriptase polymerase chain reaction analysis; MAP kinase activity; tissue growth; cell proliferation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
35
Recensione:
Indirizzi per estratti:
Indirizzo: Heron, A Fac sci Pharmaceut & Biol, Physiol Lab, 4 Ave Observ, F-75006 Paris, France Fac sci Pharmaceut & Biol 4 Ave Observ Paris France F-75006 ance
Citazione:
A. Heron et al., "Expression analysis of the histamine H-3 receptor in developing rat tissues", MECH DEVEL, 105(1-2), 2001, pp. 167-173

Abstract

Endogenous histamine is involved in tissue growth and cell proliferation. In accordance with a putative function of the H-3 receptor in this mitogenic effect, we show that H-3-receptor mRNAs are expressed together with thoseof the histamine-synthesizing enzyme in the embryonic liver and adipose tissue, and in various epithelia. Finally, we show that activation of recombinant H3 receptors enhances MAP kinase activity. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/09/20 alle ore 21:59:00