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Titolo:
Optimal dose of Gd-DTPA in dynamic MR studies
Autore:
Rusinek, H; Lee, VS; Johnson, G;
Indirizzi:
NYU, Sch Med, Dept Radiol, New York, NY USA NYU New York NY USANYU, Sch Med, Dept Radiol, New York, NY USA
Titolo Testata:
MAGNETIC RESONANCE IN MEDICINE
fascicolo: 2, volume: 46, anno: 2001,
pagine: 312 - 316
SICI:
0740-3194(200108)46:2<312:ODOGID>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
GLOMERULAR-FILTRATION RATE; DECONVOLUTION; FEASIBILITY; RENOGRAPHY; DIAGNOSIS;
Keywords:
dose of Gd-DTPA; concentration of Gd-DTPA; dynamic MR imaging; error analysis;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
16
Recensione:
Indirizzi per estratti:
Indirizzo: Rusinek, H Bellevue C&D, Rm D120,550 1st Ave, New York, NY 10016 USA Bellevue C&D Rm D120,550 1st Ave New York NY USA 10016 0016 USA
Citazione:
H. Rusinek et al., "Optimal dose of Gd-DTPA in dynamic MR studies", MAGN RES M, 46(2), 2001, pp. 312-316

Abstract

The relationship between the administered dose d of Gd-DTPA and the accuracy of measurements of the glomerular filtration rate G and the cardiac output O was investigated. For a wide range of values the concentration of Gd-DTPA can be uniquely derived from MR signals and precontrast longitudinal relaxation time. Fixed and random errors in these measured variables were analyzed. Depending on noise level and the level of renal function, errors in G reach a minimum for d = 1.4-2.8 mmol. Random errors in G are relatively insensitive to d as long as d > 1.5 mmol. These results establish the feasibility of dynamic MR measurements using doses of Gd-DTPA that are several times lower than current standards. (C) 2001 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 23:04:29