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Titolo:
Knowledge about vaccine trials and willingness to participate in an HIV/AIDS vaccine study in the Ugandan military
Autore:
McGrath, JW; George, K; Svilar, G; Ihler, E; Mafigiri, D; Kabugo, M; Mugisha, E;
Indirizzi:
Case Western Reserve Univ, Dept Anthropol, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA Family Hlth Int, Res Triangle Pk, NC 27709 USA Family Hlth Int Res Triangle Pk NC USA 27709 es Triangle Pk, NC 27709 USA Case Western Reserve Univ, Sch Med, Dept Epidemiol & Biostat, Cleveland, OH 44106 USA Case Western Reserve Univ Cleveland OH USA 44106 Cleveland, OH 44106 USA MRC, Kampala, Uganda MRC Kampala UgandaMRC, Kampala, Uganda Uganda Natl Social Secur Fund, Kampala, Uganda Uganda Natl Social Secur Fund Kampala Uganda ecur Fund, Kampala, Uganda Uganda Joint Clin Res Ctr, Kampala, Uganda Uganda Joint Clin Res Ctr Kampala Uganda Clin Res Ctr, Kampala, Uganda
Titolo Testata:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
fascicolo: 4, volume: 27, anno: 2001,
pagine: 381 - 388
SICI:
1525-4135(20010801)27:4<381:KAVTAW>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
NEW-YORK-CITY; CLINICAL-TRIALS; EFFICACY TRIALS; HIV-INFECTION; RISK; MEN; ACCEPTABILITY; ATTITUDES; THAILAND; VOLUNTEERS;
Keywords:
HIV vaccine trials; informed consent; Uganda; willingness to participate;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: McGrath, JW Case Western Reserve Univ, Dept Anthropol, 10900 Euclid Ave, Cleveland, OH44106 USA Case Western Reserve Univ 10900 Euclid Ave Cleveland OH USA 44106
Citazione:
J.W. McGrath et al., "Knowledge about vaccine trials and willingness to participate in an HIV/AIDS vaccine study in the Ugandan military", J ACQ IMM D, 27(4), 2001, pp. 381-388

Abstract

In preparation for HIV vaccine trials, knowledge about vaccines, willingness to participate in a vaccine study, and motivations for participation must be assessed. The Preparation for AIDS Vaccine Evaluation study assessed knowledge about vaccines and vaccine trials and willingness to participate in a hypothetical trial in 1,182 Ugandan military men (aged 18-30 years). Participants received education about vaccine trials and were interviewed during 24 months of follow-up observation. Its key findings are that: 1) throughout follow-up, most participants expressed willingness to participate in a hypothetical HIV vaccine trial; 2) participants are familiar with vaccines but do not clearly distinguish the use of vaccines for prevention or curing; 3) the most common reason given for being interested in participating in a vaccine trial was to be protected from HIV/AIDS; 4) trials' procedures (e.g., placebos, randomization, and blinding) were unfamiliar. and 5) knowledge about trials' procedures increased incrementally over follow-up, but at different rates for different concepts. These data demonstrate that potential vaccine trials' participants may benefit from vaccine trial education if adequate time is allowed to ensure that participants are able to master the complex information required for trial participation.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 19/01/20 alle ore 06:15:08