Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly
Autore:
Manes, F; Jorge, R; Morcuende, M; Yamada, T; Paradiso, S; Robinson, RG;
Indirizzi:
Univ Iowa, Coll Med, Dept Psychiat, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 , Dept Psychiat, Iowa City, IA 52242 USA Univ Iowa, Coll Med, Dept Neurol, Iowa City, IA 52242 USA Univ Iowa Iowa City IA USA 52242 ed, Dept Neurol, Iowa City, IA 52242 USA
Titolo Testata:
INTERNATIONAL PSYCHOGERIATRICS
fascicolo: 2, volume: 13, anno: 2001,
pagine: 225 - 231
SICI:
1041-6102(200106)13:2<225:ACSORT>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
MAJOR DEPRESSION; RESISTANT DEPRESSION; RTMS; TRIAL; MOOD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Robinson, RG Univ Iowa, Coll Med, Dept Psychiat, 200 Hawkins Dr, Iowa City, IA 52242 USA Univ Iowa 200 Hawkins Dr Iowa City IA USA 52242 IA 52242 USA
Citazione:
F. Manes et al., "A controlled study of repetitive transcranial magnetic stimulation as a treatment of depression in the elderly", INT PSYCHOG, 13(2), 2001, pp. 225-231

Abstract

Rapid transcranial magnetic stimulation (rTMS) applied to the left dorsal lateral frontal cortex has been shown to produce antidepressant effects. Older depressed patients, however, in one study showed a lower response rate than younger patients. The current study examined treatment response in 20 depressed, treatment-refractory patients (mean age 60.7 +/-9.8 years) givenfive sessions of rTMS at 20 Hz for 2 seconds over 20 trains at 80% of motor threshold or identical placebo stimulation, after patients had been withdrawn from their antidepressants. There were no significant differences in Hamilton Depression Scale scores either before or after treatment at 7 days'follow-up. There were three responders to active treatment and three to sham treatment and responders had significantly greater frontal lobe volume than nonresponders; (p = .03). These findings suggest that the stimulation parameters used in this study were probably insufficient to produce treatment response and that frontal atrophy may interfere with the effectiveness ofrTMS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:25:14