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Titolo:
Surgical treatment for non-dilated biliary tract with pancreaticobiliary maljunction should include excision of the extrahepatic bile duct
Autore:
Hara, H; Morita, S; Ishibashi, T; Sako, S; Dohi, T; Iwamoto, M; Tanigawa, N;
Indirizzi:
Osaka Med Coll, Dept Gen & Gastroenterol Surg, Takatsuki, Osaka 5698686, Japan Osaka Med Coll Takatsuki Osaka Japan 5698686 atsuki, Osaka 5698686, Japan
Titolo Testata:
HEPATO-GASTROENTEROLOGY
fascicolo: 40, volume: 48, anno: 2001,
pagine: 984 - 987
SICI:
0172-6390(200107/08)48:40<984:STFNBT>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHOLEDOCHAL CYST; POINT MUTATIONS; RAS GENE; K-RAS; GALLBLADDER; CARCINOMA; JUNCTION; EPITHELIUM;
Keywords:
non-dilated biliary tract; pancreaticobiliary maljunction; surgical treatment;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Hara, H Osaka Med Coll, Dept Gen & Gastroenterol Surg, 2-7 Daigaku Machi, Takatsuki, Osaka 5698686, Japan Osaka Med Coll 2-7 Daigaku Machi Takatsuki Osaka Japan 5698686 pan
Citazione:
H. Hara et al., "Surgical treatment for non-dilated biliary tract with pancreaticobiliary maljunction should include excision of the extrahepatic bile duct", HEP-GASTRO, 48(40), 2001, pp. 984-987

Abstract

Background/Aims: The authors evaluated the surgical treatment for non-dilated biliary tract with pancreaticobiliary maljunction. Methodology: Sixty-nine patients with pancreaticobiliary maljunction were divided into 61 patients with the dilated biliary tract and 8 with the nondilated biliary tract. The levels of amylase activity in the bile in the gallbladder and the bile duct, the incidence and severity of postoperative cholangitis, and cell proliferating activity of the biliary tract epithelium, examined the proliferating cell nuclear antigen labeling index (PCNALI), were examined. Results: Of the 61 dilated type patients, 12 were of Ia, 1 was of Ib, 22 were of Ic, 25 were of W-A, and 1 was of IV-B according to Todani's classification. Cancer was detected in 7 dilated type patients and in 3 non-dilatedtype patients. A high level of amylase activity was measured in the bile juice in both the gallbladder and bile duct in all of the patients with pancreaticobiliary maljunction. PCNALI of the biliary tract epithelium of the patients without cancer (dilated type: bile duct 11.4%, gallbladder 12.7%; non-dilated type: bile duct 5.9%, gallbladder 13.8%) was higher than that ofthe patients without pancreaticobiliary malfunction (bile duct 1.5%, gallbladder 1.4%). Conclusions: In a non-dilated type, as well as in a dilated type, a high level of amylase activity and increase of cell proliferative activity of thebiliary tract epithelium were observed. Therefore, these results suggest that the extrahepatic bile duct should be prophylactically removed in patients with nondilated type as well as in those with dilated type pancreaticobiliary maljunction.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 16:03:04