Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
First-trimester biochemical screening for Down syndrome
Autore:
Yaron, Y; Mashiach, R;
Indirizzi:
Lis Matern Hosp, Tel Aviv Sourasky Med Ctr, Inst Genet, Prenatal Diag Unit, Tel Aviv, Israel Lis Matern Hosp Tel Aviv Israel t, Prenatal Diag Unit, Tel Aviv, Israel Lis Matern Hosp, Tel Aviv Sourasky Med Ctr, Dept Obstet & Gynecol, Tel Aviv, Israel Lis Matern Hosp Tel Aviv Israel Dept Obstet & Gynecol, Tel Aviv, Israel Tel Aviv Univ, Sackler Fac Med, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 ac Med, IL-69978 Tel Aviv, Israel
Titolo Testata:
CLINICS IN PERINATOLOGY
fascicolo: 2, volume: 28, anno: 2001,
pagine: 321 -
SICI:
0095-5108(200106)28:2<321:FBSFDS>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
PLASMA-PROTEIN-A; FETAL NUCHAL TRANSLUCENCY; HUMAN CHORIONIC-GONADOTROPIN; FREE-BETA-HCG; SERUM IMMUNOREACTIVE INHIBIN; MATERNAL SERUM; ALPHA-FETOPROTEIN; EARLY-PREGNANCY; 2ND TRIMESTERS; CHROMOSOMAL-ABNORMALITIES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
53
Recensione:
Indirizzi per estratti:
Indirizzo: Yaron, Y Sourasky Med Ctr, Genet Inst, Prenatal Diag Unit, 6 Weizmann St, IL-64239 Tel Aviv, Israel Sourasky Med Ctr 6 Weizmann St Tel Aviv Israel IL-64239 , Israel
Citazione:
Y. Yaron e R. Mashiach, "First-trimester biochemical screening for Down syndrome", CLIN PERIN, 28(2), 2001, pp. 321

Abstract

Of all markers evaluated for first-trimester biochemical screening for Down syndrome (DS), PAPP-A and free beta -hCG emerged as the most predictive. The combined test uses these markers in AV conjunction with nuchal translucency measurements, and is estimated to achieve a DS detection rate of 80% to 85% at a 5% false-positive rate. The integrated test, combining first-trimester sonographic and biochemical markers with second-trimester markers, provides a single estimate of a patients DS risk, and may yield a DS detection rate of 94% at a 5% false-positive rate. The acceptability and feasibility of this test, however, remain to be proved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/09/20 alle ore 09:31:27