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Titolo:
Macronutrients and appetite control with implications for the nutritional management of the malnourished
Autore:
Stubbs, RJ; Elia, M;
Indirizzi:
Rowett Res Inst, Aberdeen AB21 9SB, Scotland Rowett Res Inst Aberdeen Scotland AB21 9SB , Aberdeen AB21 9SB, Scotland Addenbrookes Hosp, Cambridge, England Addenbrookes Hosp Cambridge England denbrookes Hosp, Cambridge, England
Titolo Testata:
CLINICAL NUTRITION
, volume: 20, anno: 2001, supplemento:, 1
pagine: 129 - 139
SICI:
0261-5614(200106)20:<129:MAACWI>2.0.ZU;2-F
Fonte:
ISI
Lingua:
ENG
Soggetto:
FOOD-INTAKE; ENERGY-BALANCE; COVERT MANIPULATION; CLINICAL-PRACTICE; AD-LIBITUM; FAT; CARBOHYDRATE; PROTEIN; LIPOGENESIS; HUMANS;
Keywords:
macronutrients; appetite; satiety; energy balance; undernutrition; obesity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
71
Recensione:
Indirizzi per estratti:
Indirizzo: Stubbs, RJ Rowett Res Inst, Aberdeen AB21 9SB, Scotland Rowett Res Inst Aberdeen Scotland AB21 9SB AB21 9SB, Scotland
Citazione:
R.J. Stubbs e M. Elia, "Macronutrients and appetite control with implications for the nutritional management of the malnourished", CLIN NUTR, 20, 2001, pp. 129-139

Abstract

Altered appetite is one of the most frequently cited yet poorly understoodsymptoms encountered in the clinical setting. This review critically discusses the constraints under which macronutrient balance is physiologically regulated, the nature of appetite control and feeding behaviour in humans, how dietary macronutrients influence appetite control and feeding behaviour,the role of macronutrient metabolism and stores as putative signals that can influence appetite, energy intake and balance, and the importance of studying undernutrition as a reference for studies of appetite in the clinicalsetting in order to develop effective therapies for malnutrition (over andundernutrition). The following general conclusions were reached: (1) thereseems to be a hierarchy in the extent to which individual macronutrient balances are regulated and the extent to which dietary macronutrients suppress subsequent energy intake (in both cases protein > carbohydrate > fat); (2) the oxidation of individual nutrients is monitored both by the central and peripheral nervous system but the relative importance of the two systems is unclear; (3) recent work on body weight regulation has placed much more emphasis on signals arising from adipose tissue than other potentially powerful signals arising from lean tissue; (4) in disease-related malnutrition,loss of both lean and adipose tissue is often not associated with increased appetite sensations and food intake probably because of complex interactions between inflammatory mediators such as cytokines, neuroendocrine abnormalities, drug (and other) therapies, and incompletely understood effects ofpsychological and metabolic disturbances. (C) 2001 Harcourt Publishers Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/07/20 alle ore 20:44:51