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Titolo:
Therapeutic application of repetitive transcranial magnetic stimulation: areview
Autore:
Wassermann, EM; Lisanby, SH;
Indirizzi:
NINDS, Brain Stimulat Unit, Bethesda, MD 20892 USA NINDS Bethesda MD USA 20892 , Brain Stimulat Unit, Bethesda, MD 20892 USA Columbia Univ, Coll Phys & Surg, New York State Psychiat Inst, Dept Biol Psychiat, New York, NY USA Columbia Univ New York NY USA Inst, Dept Biol Psychiat, New York, NY USA Columbia Univ, Coll Phys & Surg, Dept Psychiat, New York, NY USA Columbia Univ New York NY USA ys & Surg, Dept Psychiat, New York, NY USA
Titolo Testata:
CLINICAL NEUROPHYSIOLOGY
fascicolo: 8, volume: 112, anno: 2001,
pagine: 1367 - 1377
SICI:
1388-2457(200108)112:8<1367:TAORTM>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
DORSOLATERAL PREFRONTAL CORTEX; OBSESSIVE-COMPULSIVE DISORDER; REFRACTORY DEPRESSED-PATIENTS; RESISTANT MAJOR DEPRESSION; AMYGDALA-KINDLED SEIZURES; LONG-TERM POTENTIATION; HUMAN MOTOR CORTEX; RAT-BRAIN; ELECTROCONVULSIVE-THERAPY; PARKINSONS-DISEASE;
Keywords:
depression; Parkinson's disease; treatment; clinical trials; motor cortex; prefrontal cortex;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
123
Recensione:
Indirizzi per estratti:
Indirizzo: Wassermann, EM NINDS, Brain Stimulat Unit, 10 Ctr Dr MSC 1428, Bethesda, MD 20892 USA NINDS 10 Ctr Dr MSC 1428 Bethesda MD USA 20892 MD 20892 USA
Citazione:
E.M. Wassermann e S.H. Lisanby, "Therapeutic application of repetitive transcranial magnetic stimulation: areview", CLIN NEU, 112(8), 2001, pp. 1367-1377

Abstract

Transcranial magnetic stimulation (TMS), a non-invasive means of electrically stimulating neurons in the human cerebral cortex, is able to modify neuronal activity locally and at distant sites when delivered in series or trains of pulses. Data from stimulation of the motor cortex suggest that the type of effect on the excitability of the cortical network depends on the frequency of stimulation. These data, as well as results from studies in rodents, have been generalized across brain areas and species to provide rationales for using repetitive TMS (rTMS) to treat various brain disorders, mostnotably depression. Research into clinical applications for TMS remains active and has the potential to provide useful data, but, to date, the results of blinded, sham-controlled trials do not provide clear evidence of beneficial effects that replace or even match the effectiveness of conventional treatments in any disorder. In this review, we discuss the clinical and scientific bases for using rTMS as treatment, and review the results of trialsin psychiatric and neurological disorders to date. (C) 2001 Elsevier Science Ireland Ltd. AE rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:59:11