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Titolo:
Melanoma risk in relation to height, weight, and exercise (United States)
Autore:
Shors, AR; Solomon, C; McTiernan, A; White, E;
Indirizzi:
Fred Hutchinson Canc Res Ctr, Canc Prevent Res Program, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr Seattle WA USA 98109 , Seattle, WA 98109 USA Univ Washington, Sch Publ Hlth, Dept Epidemiol, Seattle, WA 98195 USA UnivWashington Seattle WA USA 98195 ept Epidemiol, Seattle, WA 98195 USA Univ Washington, Sch Med, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 gton, Sch Med, Seattle, WA 98195 USA Univ Washington, Med Ctr, Dept Med, Div Gen Internal Med, Seattle, WA 98195 USA Univ Washington Seattle WA USA 98195 Internal Med, Seattle, WA 98195 USA
Titolo Testata:
CANCER CAUSES & CONTROL
fascicolo: 7, volume: 12, anno: 2001,
pagine: 599 - 606
SICI:
0957-5243(200109)12:7<599:MRIRTH>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
CUTANEOUS MALIGNANT-MELANOMA; WESTERN-CANADA-MELANOMA; BREAST-CANCER RISK; PHYSICAL-ACTIVITY; REPRODUCTIVE FACTORS; GROWTH-HORMONE; BODY-SIZE; WOMEN; MELATONIN; SEX;
Keywords:
exercise; height; melanoma; obesity; weight;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: White, E Fred Hutchinson Canc Res Ctr, Canc Prevent Res Program, MP 702,POB 19024, Seattle, WA 98109 USA Fred Hutchinson Canc Res Ctr MP 702,POB 19024 Seattle WA USA 98109
Citazione:
A.R. Shors et al., "Melanoma risk in relation to height, weight, and exercise (United States)", CANC CAUSE, 12(7), 2001, pp. 599-606

Abstract

Height and weight and derivations thereof are positively associated with anumber of cancers. While several authors have reported an increased risk of melanoma among people at the higher extremes of these measures, the association has not been fully explored. New cases of primary cutaneous melanomain 1997 in western Washington State (n = 386) were compared to controls selected by random-digit dialing (n = 727). Each study participant completed a telephone survey, and data were collected on height, weight, sun-related melanoma risk factors, demographic characteristics, as well as habits such as diet and exercise. Risk of melanoma was analyzed by logistic regression with adjustment for age, hair color, lifetime sun exposure, and fruit and vegetable intake. An excess risk of melanoma was identified in men in the upper quartiles of height (OR = 2.4, 95% confidence interval (CI) = 1.3-4.5),weight (OR = 2.8, CI = 1.5-5.2), and body surface area (OR = 2.8, CI = 1.5-5.1) vs. the lowest quartiles. In women, no association was present for any anthropometric measure. In addition, we found that men and women exercising five to seven days per week were at a decreased risk of melanoma (OR = 0.7, CI = 0.5-1.0). The anthropometric findings are largely consistent with previous studies, while this is the first report of an association of exercise with melanoma risk. The mechanisms for the effect of exercise and for the difference between men and women in the effect of anthropometric factorsare unknown. Future research in basic and epidemiologic science should focus on biochemical or behavioral explanations for these observations.

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Documento generato il 02/04/20 alle ore 02:32:41