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Titolo:
Comparison of virulence and restriction endonuclease cleavage patterns of infectious laryngotracheitis viruses isolated in Korea
Autore:
Han, MG; Kim, SJ;
Indirizzi:
Natl Vet Res & Quarantine Serv, Anim Dis Res Dept, Avian Dis Div, Anyang 430824, Kyunggi, South Korea Natl Vet Res & Quarantine Serv Anyang Kyunggi South Korea 430824 th Korea Seoul Natl Univ, Coll Vet Med, Suwon 441744, Kyunggi, South Korea Seoul Natl Univ Suwon Kyunggi South Korea 441744 44, Kyunggi, South Korea
Titolo Testata:
AVIAN PATHOLOGY
fascicolo: 4, volume: 30, anno: 2001,
pagine: 337 - 344
SICI:
0307-9457(200108)30:4<337:COVARE>2.0.ZU;2-3
Fonte:
ISI
Lingua:
ENG
Soggetto:
LIVE VACCINE VIRUSES; STRAINS; RECOMBINANTS; CHICKENS; DIFFERENTIATION; LATENCY;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Han, MG Natl Vet Res & Quarantine Serv, Anim Dis Res Dept, Avian Dis Div, 480, Anyang 430824, Kyunggi, South Korea Natl Vet Res & Quarantine Serv 480Anyang Kyunggi South Korea 430824
Citazione:
M.G. Han e S.J. Kim, "Comparison of virulence and restriction endonuclease cleavage patterns of infectious laryngotracheitis viruses isolated in Korea", AVIAN PATH, 30(4), 2001, pp. 337-344

Abstract

Isolates of infectious laryngotracheitis virus ( ILTV) obtained from fielddisease outbreaks in Korea from 1982 to 1998 were compared by virulence testing and by examining restriction endonuclease (REN) cleavage patterns of viral DNA. Based on pathogenicity tests, eight of 11 ILTV strains were classified as virulent, because these strains caused 40 to 80% mortality in specific pathogen free chickens, while three strains were classified as low virulence because these did not cause mortality. The REN cleavage patterns ofthe low virulence strains were identical with those of two reference vaccine strains, which were of chicken embryo origin. However, the DNA cleavage patterns of the virulent strains differed from those of both the low virulence and the vaccine strains. Furthermore, one virulent Korean strain N87278had REN cleavage patterns that were clearly different from other virulent strains. In the present study, ILTV strains examined could be classified into two groups (virulent and low virulence strains) by pathogenicity testing, and three groups based on their REN cleavage patterns. These results suggest that most outbreaks of infectious laryngotracheitis were not likely to be associated with vaccine strains, but some were associated with viruses indistinguishable from commercial vaccine strains. At least three genetically distinct groupings of ILTV have been involved in outbreaks of infectious laryngotracheitis in Korea.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 23:06:49