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Titolo:
Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure
Autore:
Jiang, W; Alexander, J; Christopher, E; Kuchibhatla, M; Gaulden, LH; Cuffe, MS; Blazing, MA; Davenport, C; Califf, RM; Krishnan, RR; OConnor, CM;
Indirizzi:
Duke Univ, Med Ctr, Dept Psychiat, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 ed Ctr, Dept Psychiat, Durham, NC 27710 USA Duke Univ, Med Ctr, Dept Med, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 iv, Med Ctr, Dept Med, Durham, NC 27710 USA Duke Univ, Med Ctr, Div Biometry, Durham, NC 27710 USA Duke Univ Durham NC USA 27710 Med Ctr, Div Biometry, Durham, NC 27710 USA Duke Univ, Med Ctr, Dept Community & Family Med, Durham, NC 27710 USA DukeUniv Durham NC USA 27710 ommunity & Family Med, Durham, NC 27710 USA
Titolo Testata:
ARCHIVES OF INTERNAL MEDICINE
fascicolo: 15, volume: 161, anno: 2001,
pagine: 1849 - 1856
SICI:
0003-9926(20010813)161:15<1849:RODTIR>2.0.ZU;2-Q
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORONARY-ARTERY DISEASE; ACUTE MYOCARDIAL-INFARCTION; RATE-VARIABILITY; MAJOR DEPRESSION; ELDERLY PATIENTS; FUNCTIONAL STATUS; SOCIAL SUPPORT; ASSOCIATION; PROGNOSIS; VARIABLES;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
43
Recensione:
Indirizzi per estratti:
Indirizzo: Jiang, W 3203 Winfield Dr, Durham, NC 27707 USA 3203 Winfield Dr Durham NC USA 27707 ld Dr, Durham, NC 27707 USA
Citazione:
W. Jiang et al., "Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure", ARCH IN MED, 161(15), 2001, pp. 1849-1856

Abstract

Background: Patients with congestive heart failure (CHF) may have a high prevalence of depression, which may increase the risk of adverse outcomes. Objective: To determine the prevalence and relationship of depression to outcomes of patients hospitalized with CHF. Methods: We screened patients aged 18 years or older having New York HeartAssociation class II or greater CHF, an ejection fraction of 35% or less, or both, admitted between March 1, 1997, and June 30, 1998, to the cardiology service of one hospital. Patients with a Beck Depression Inventory scoreof 10 or higher underwent a modified National Institute of Mental Health Diagnostic Interview Schedule to identify major depressive disorder. Primarycare providers coordinated standard treatment for CHF and other medical and psychiatric disorders. We assessed all-cause mortality and readmission (rehospitalization) rates 3 months and 1 year after depression assessment. Logistic regression analyses were used to evaluate the independent prognosticvalue of depression after adjustment for clinical risk factors. Results: Of 374 patients screened, 35.3% had a Beck Depression Inventory score of 10 or higher and 13.9% had major depressive disorder. Overall mortality was 7.9% at 3 months and 16.2% at I year. Major depression was associated with increased mortality at 3 months (odds ratio, 2.5 vs no depression;P = .08) and at 1 year (odds ratio, 2.23; P = .04) and readmission at 3 months (odds ratio, 1.90; P = .04) and at 1 year (odds ratio, 3.07; P = .005). These increased risks were independent of age, New York Heart Associationclass, baseline ejection fraction, and ischemic etiology of CHF. Conclusions: Major depression is common in patients hospitalized with CHF and is independently associated with a poor prognosis.

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Documento generato il 26/01/20 alle ore 09:59:24