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Titolo:
Fuel ethanol production from lignocellulose: a challenge for metabolic engineering and process integration
Autore:
Zaldivar, J; Nielsen, J; Olsson, L;
Indirizzi:
Tech Univ Denmark, Dept Biotechnol, Ctr Proc Biotechnol, DK-2800 Kgs Lyngby, Denmark Tech Univ Denmark Kgs Lyngby Denmark DK-2800 DK-2800 Kgs Lyngby, Denmark
Titolo Testata:
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
fascicolo: 1-2, volume: 56, anno: 2001,
pagine: 17 - 34
SICI:
0175-7598(200107)56:1-2<17:FEPFLA>2.0.ZU;2-7
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECOMBINANT ESCHERICHIA-COLI; ALCOHOL DEHYDROGENASE-II; ZYMOMONAS-MOBILIS GENES; MEMBRANE H+-ATPASE; SACCHAROMYCES-CEREVISIAE; XYLOSE FERMENTATION; CLOSTRIDIUM-THERMOHYDROSULFURICUM; HEMICELLULOSE HYDROLYSATE; ANAEROBIC-BACTERIA; PENTOSE METABOLISM;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
155
Recensione:
Indirizzi per estratti:
Indirizzo: Nielsen, J Tech Univ Denmark, Dept Biotechnol, Ctr Proc Biotechnol, Bldg 223, DK-2800Kgs Lyngby, Denmark Tech Univ Denmark Bldg 223 Kgs Lyngby Denmark DK-2800 Denmark
Citazione:
J. Zaldivar et al., "Fuel ethanol production from lignocellulose: a challenge for metabolic engineering and process integration", APPL MICR B, 56(1-2), 2001, pp. 17-34

Abstract

With industrial development growing rapidly, there is a need for environmentally sustainable energy sources. Bioethanol (ethanol from biomass) is an attractive, sustainable energy source to fuel transportation. Based on the premise that fuel bioethanol can contribute to a cleaner environment and with the implementation of environmental protection laws in many countries, demand for this fuel is increasing. Efficient ethanol production processes and cheap substrates are needed. Current ethanol production processes using crops such as sugar cane and corn are well-established; however, utilization of a cheaper substrate such as lignocellulose could make bioethanol more competitive with fossil fuel. The processing and utilization of this substrate is complex, differing, in many aspects from crop-based ethanol production. One important requirement is an efficient microorganism able to fermenta variety of sugars (pentoses, and hexoses) as well as to tolerate stress conditions. Through metabolic engineering, bacterial and yeast strains havebeen constructed which feature traits that are advantageous for ethanol production using lignocellulose sugars. After several rounds of modification/evaluation/modification, three main microbial platforms, Saccharomyces cerevisiae, Zymomonas mobilis, and Escherichia coli, have emerged and they haveperformed well in pilot studies. While there are ongoing efforts to further enhance their properties, improvement of the fermentation process is justone of several factors that needs to be fully optimized and integrated to generate a competitive lignocellulose ethanol plant.

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Documento generato il 31/03/20 alle ore 05:07:21