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Titolo:
Auditory evoked potential index predicts the depth of sedation and movement in response to skin incision during sevoflurane anesthesia
Autore:
Kurita, T; Doi, M; Katoh, T; Sano, H; Sato, S; Mantzaridis, H; Kenny, GNC;
Indirizzi:
Hamamatsu Univ, Sch Med, Dept Anesthesiol & Intens Care, Hamamatsu, Shizuoka 4313192, Japan Hamamatsu Univ Hamamatsu Shizuoka Japan 4313192 , Shizuoka 4313192, Japan
Titolo Testata:
ANESTHESIOLOGY
fascicolo: 2, volume: 95, anno: 2001,
pagine: 364 - 370
SICI:
0003-3022(200108)95:2<364:AEPIPT>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
SPECTRAL EDGE FREQUENCY; NITROUS-OXIDE ANESTHESIA; REPEATED TRANSITIONS; PROPOFOL ANESTHESIA; BISPECTRAL ANALYSIS; MEDIAN FREQUENCY; EEG BISPECTRUM; ISOFLURANE; VOLUNTEERS; HUMANS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Kurita, T Hamamatsu Univ, Sch Med, Dept Anesthesiol & Intens Care, 3600 Handa Cho, Hamamatsu, Shizuoka 4313192, Japan Hamamatsu Univ 3600 Handa Cho Hamamatsu Shizuoka Japan 4313192 n
Citazione:
T. Kurita et al., "Auditory evoked potential index predicts the depth of sedation and movement in response to skin incision during sevoflurane anesthesia", ANESTHESIOL, 95(2), 2001, pp. 364-370

Abstract

Background: The auditory evoked potential (AEP) index, which is a single numerical parameter derived from the AEP in real time and which describes the underlying morphology of the AEP, has been studied as a monitor of anesthetic depth. The current study was designed to evaluate the accuracy of AEPindex for predicting depth of sedation and anesthesia during sevoflurane anesthesia. Methods. In the first phase of the study, a single end-tidal sevoflurane concentration ranging from 0.5 to 0.9% was assigned randomly and administered to each of 50 patients. The AEPindex and the Bispectral Index (BIS) were obtained simultaneously. Sedation was assessed using the responsiveness portion of the observer's assessment of alertness-sedation scale. in the second phase of the study, 10 additional patients were included, and the 60 patients who were scheduled to have skin incisions were observed for movement in response to skin incision at the end-tidal sevoflurane concentrations between 1.6 and 2.6%. The relation among AEPindex, BIS, sevoflurane concentration, sedation score, and movement or absence of movement after skin incision was determined. Prediction probability values for AEPindex, BIS, and sevoflurane concentration to predict depth of sedation and anesthesia were alsocalculated. Results: The AEPindex, BIS, and sevoflurane concentration correlated closely with the sedation score. The prediction probability values for AEPindex,BIS, and sevoflurane concentration for sedation score were 0.820, 0.805, and 0.870,respectively, indicating a high predictive performance for depth of sedation. AEPindex and sevoflurane concentration successfully predicted movement after skin (prediction probability = 0.910 and 0.857, respectively), whereas BIS could not (prediction probability = 0.537). Conclusions. Auditory evoked potential index can be a guide to the depth of sedation and movement in response to skin incision during sevoflurane anesthesia.

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Documento generato il 15/07/20 alle ore 14:43:31