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Titolo:
Effects of dexamethasone on emesis in cats sedated with xylazine hydrochloride
Autore:
Ho, CM; Ho, ST; Wang, JJ; Lee, TY; Chai, CY;
Indirizzi:
Natl Def Med Ctr, Grad Inst Med Sci, Taipei 114, Taiwan Natl Def Med Ctr Taipei Taiwan 114 Grad Inst Med Sci, Taipei 114, Taiwan Natl Def Med Ctr, Dept Anesthesiol, Taipei 114, Taiwan Natl Def Med Ctr Taipei Taiwan 114 Dept Anesthesiol, Taipei 114, Taiwan Taipei Vet Gen Hosp, Dept Anesthesiol, Taipei 112, Taiwan Taipei Vet Gen Hosp Taipei Taiwan 112 pt Anesthesiol, Taipei 112, Taiwan Chi Mei Med Ctr, Dept Anesthesiol, Tainan 710, Taiwan Chi Mei Med Ctr Tainan Taiwan 710 , Dept Anesthesiol, Tainan 710, Taiwan Acad Sinica, Inst Biomed Sci, Taipei 115, Taiwan Acad Sinica Taipei Taiwan 115 inica, Inst Biomed Sci, Taipei 115, Taiwan
Titolo Testata:
AMERICAN JOURNAL OF VETERINARY RESEARCH
fascicolo: 8, volume: 62, anno: 2001,
pagine: 1218 - 1221
SICI:
0002-9645(200108)62:8<1218:EODOEI>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CISPLATIN-INDUCED EMESIS; POSTOPERATIVE NAUSEA; DELAYED EMESIS; CHEMOTHERAPY; YOHIMBINE; ONDANSETRON; PROPHYLAXIS; SINGLE; DOGS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Ho, ST Natl Def Med Ctr, Grad Inst Med Sci, Minchiuan E Rd, Taipei 114, Taiwan Natl Def Med Ctr Minchiuan E Rd Taipei Taiwan 114 ipei 114, Taiwan
Citazione:
C.M. Ho et al., "Effects of dexamethasone on emesis in cats sedated with xylazine hydrochloride", AM J VET RE, 62(8), 2001, pp. 1218-1221

Abstract

Objective To determine antiemetic efficacy of prophylactic administration of dexamethasone and its influence on sedation in cats sedated with xylazine hydrochloride. Animals-6 healthy adult cats (3 males and 3 females). Procedure-The prophylactic antiemetic effect of 4 doses of dexamethasone (1, 2, 4, and 8 mg/kg of body weight, IM) or saline (0.9% NaCl) solution (0.066 ml/kg, IM) administered 1 hour before administration of xylazine (0.66 mg/kg, IM) was evaluated. Cats initially were given saline treatment (day 0) and were given sequentially increasing doses of xylazine on days 7, 14, 21, and 28. After xylazine injection, all cats were observed for 30 minutes to allow assessment of frequency of emesis and time until onset of the first emetic episode. The influence of dexamethasone on xylazine-induced sedation in these cats also was evaluated. Results-Prior treatment with 4 or 8 mg/kg of dexamethasone significantly reduced the frequency of emetic episodes and also significantly prolonged the time until onset of the first emetic episode after xylazine injection. Time until onset of the first emetic episode also was significantly prolongedfor dexamethasone at a dose of 2 mg/kg. Time until onset of sedation afteradministration of xylazine was not altered by administration of dexamethasone. Conclusions and Clinical Relevance-Dexamethasone (4 or 8 mg/kg, IM) significantly decreased the frequency of emetic episodes induced by xylazine without compromising sedative effects in cats. Dexamethasone may be used prophylactically as an antiemetic in cats treated with xylazine.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 16:52:01