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Titolo:
High NK cell activity in early pregnancy correlates with subsequent abortion with normal chromosomes in women with recurrent abortion
Autore:
Yamada, H; Kato, EH; Kobashi, G; Ebina, Y; Shimada, S; Morikawa, M; Sakuragi, N; Fujimoto, S;
Indirizzi:
Hokkaido Univ, Sch Med, Dept Obstet & Gynecol, Kita Ku, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608638 oro, Hokkaido 0608638, Japan Hokkaido Univ, Sch Med, Dept Publ Hlth, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ Sapporo Hokkaido Japan 0608638 oro, Hokkaido 0608638, Japan
Titolo Testata:
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
fascicolo: 2, volume: 46, anno: 2001,
pagine: 132 - 136
SICI:
1046-7408(200108)46:2<132:HNCAIE>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
NATURAL-KILLER-CELLS; IMMUNOTHERAPY; CYTOTOXICITY; LYMPHOCYTES; LOSSES; CD56+;
Keywords:
miscarriage; NK cell; pregnancy; recurrent spontaneous abortion;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Yamada, H Hokkaido Univ, Sch Med, Dept Obstet & Gynecol, Kita Ku, N15 W7, Sapporo, Hokkaido 0608638, Japan Hokkaido Univ N15 W7 Sapporo Hokkaido Japan 0608638 08638, Japan
Citazione:
H. Yamada et al., "High NK cell activity in early pregnancy correlates with subsequent abortion with normal chromosomes in women with recurrent abortion", AM J REPROD, 46(2), 2001, pp. 132-136

Abstract

PROBLEM: The aim of this study was to assess the role of natural killer (NK) cells in pregnant women with a history of recurrent spontaneous abortion(RSA). METHOD OF STUDY: Consecutive 66 pregnant women with a history of RSA were prospectively assessed for peripheral NK cell activity, percentage of the NK cell subsets, and subsequent pregnancy outcome. RESULTS: NK cell activity in women with subsequent live birth (group I) at4-5 gestational weeks (GW) (mean +/- SD, 32.5 +/- 12.3%) significantly decreased at 6-7 GW (28.1 +/- 12.1%) and at 8-9 GW (28.0 +/- 11.8%). NK cell activity in women with subsequent abortion with normal chromosomes (group II) at 6-7 GW (41.2 +/- 19.0%) was significantly higher than that in group I women, while NK cell activity at 6-7 GW in women with subsequent abortion with abnormal chromosomes (group III) was the same as the level in group I women. CONCLUSIONS: High NK cell activity at 6-7 GW correlates with subsequent abortion with normal chromosomes.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 26/11/20 alle ore 11:46:00