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Titolo:
Stress and pregnancy loss: Role of immune mediators, hormones and neurotransmitters
Autore:
Arck, PC;
Indirizzi:
Humboldt Univ, Berlin, Germany Humboldt Univ Berlin GermanyHumboldt Univ, Berlin, Germany
Titolo Testata:
AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY
fascicolo: 2, volume: 46, anno: 2001,
pagine: 117 - 123
SICI:
1046-7408(200108)46:2<117:SAPLRO>2.0.ZU;2-5
Fonte:
ISI
Lingua:
ENG
Soggetto:
CORTICOTROPIN-RELEASING HORMONE; PITUITARY-ADRENAL AXIS; NATURAL-KILLER-CELLS; X DBA/2 MICE; SPONTANEOUS-ABORTION; PROCOAGULANT FGL2; LEISHMANIA-MAJOR; C57BL/6 MICE; LIFE EVENTS; IFN-GAMMA;
Keywords:
abortion, hormones; neurotransmitter; preeclampsia; stress; Th1/Th2 ratio;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
65
Recensione:
Indirizzi per estratti:
Indirizzo: Arck, PC Biomed Forschungszentrum Raum 2 0549, Charite, Med Klin, Augustenburger Pl1,Campus Virchow Klinikum, D-13353 Berlin, Germany Biomed Forschungszentrum Raum 2 0549 Augustenburger Pl 1,Campus Virchow Klinikum Berlin Germany D-13353
Citazione:
P.C. Arck, "Stress and pregnancy loss: Role of immune mediators, hormones and neurotransmitters", AM J REPROD, 46(2), 2001, pp. 117-123

Abstract

This review highlights recent studies investigating the impact of stress on pregnancy health or loss. Spontaneous abortion is the most common adversepregnancy outcome, and stress has been suggested to be abortogenic in miceand humans. A wealth of information has been published on the effect of stress on the nervous, endocrine and immune systems during the past two decades. Stress- and/or pregnancy- related hormones (corticotropin releasing hormone, adrenocorticotropin, prolactin, and progesterone) might interact withperipheral and local immuncompetent cells, such as certain T cell subsets,mast cells or NK cells, and result in changes of cytokine production. Since a well-balanced interaction of nervous, endocrine and immune system is crucial for the maintenance of successful pregnancy, putative mechanisms and recent observations on stress-triggered pregnancy failure have been reviewed.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:18:19