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Titolo:
Catechin intake might explain the inverse relation between tea consumptionand ischemic heart disease: the Zutphen Elderly Study
Autore:
Arts, ICW; Hollman, PCH; Feskens, EJM; de Mesquita, HBB; Kromhout, D;
Indirizzi:
RIKILT, State Inst Qual Control Prod, NL-6700 AE Wageningen, Netherlands RIKILT Wageningen Netherlands NL-6700 AE 6700 AE Wageningen, Netherlands Natl Inst Publ Hlth & Environm, RIVM, Div Publ Hlth Res, Bilthoven, Netherlands Natl Inst Publ Hlth & Environm Bilthoven Netherlands hoven, Netherlands
Titolo Testata:
AMERICAN JOURNAL OF CLINICAL NUTRITION
fascicolo: 2, volume: 74, anno: 2001,
pagine: 227 - 232
SICI:
0002-9165(200108)74:2<227:CIMETI>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
POTENTIALLY ANTICARCINOGENIC FLAVONOIDS; MYOCARDIAL-INFARCTION; FRUIT JUICES; RISK-FACTORS; CORONARY; NETHERLANDS; MORTALITY; COFFEE; ATHEROSCLEROSIS; VEGETABLES;
Keywords:
catechin; tea; flavonoid; diet; ischemic heart disease; cerebrovascular disorders; stroke; epidemiology; cohort studies; elderly men; the Zutphen Elderly Study; Netherlands;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Arts, ICW RIKILT, ICW Arts, POB 230, NL-6700 AE Wageningen, Netherlands RIKILT POB 230 Wageningen Netherlands NL-6700 AE n, Netherlands
Citazione:
I.C.W. Arts et al., "Catechin intake might explain the inverse relation between tea consumptionand ischemic heart disease: the Zutphen Elderly Study", AM J CLIN N, 74(2), 2001, pp. 227-232

Abstract

Background: Epidemiologic studies suggest that tea consumption may reduce the risk of cardiovascular diseases, but results are inconsistent. Catechins, which belong to the flavonoid family, are the main components of tea andmay be responsible for the alleged protective effect. Taking catechin sources other than tea into account might clarify the reported associations,Objective: The objective was to evaluate the association between catechin intake and the incidence of and mortality from ischemic heart disease and stroke. Design: We evaluated the effect of a high catechin intake by using data from the Zutphen Elderly Study, a prospective cohort study of 806 men aged 65-84 y at baseline in 1985. Results: The mean (+/- SD) catechin intake at baseline was 72 +/- 47.8 mg,mainly from black tea, apples, and chocolate. A total of 90 deaths from ischemic heart disease were documented. Catechin intake was inversely associated with ischemic heart disease mortality; the multivariate-adjusted risk ratio in the highest tertile of intake was 0.49 (95% CI: 0.27 0.88; P for trend: 0.017). After multivariate adjustment, catechin intake was not associated with the incidence of myocardial infarction (risk ratio in the highest tertile of intake: 0.70; 95% CI: 0.39, 1.26; P for trend: 0.232). After adjustment for tea consumption and flavonol intake, a 7.5-mg increase in catechin intake from sources other than tea was associated with a tendency for a20% reduction in ischemic heart disease mortality risk (P = 0.114). There was no association between catechin intake and stroke incidence or mortality. Conclusion: Catechins, whether from tea or other sources, may reduce the risk of ischemic heart disease mortality but not of stroke.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 19:18:06