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Titolo:
Fetal nuchal translucency and normal chromosomes: a long-term follow-up study
Autore:
Hiippala, A; Eronen, M; Taipale, P; Salonen, R; Hiilesmaa, V;
Indirizzi:
Helsinki Univ Hosp, Hosp Children & Adolescents, FIN-00170 Helsinki, Finland Helsinki Univ Hosp Helsinki Finland FIN-00170 IN-00170 Helsinki, Finland Helsinki Univ Hosp, Dept Obstet & Gynecol, FIN-00170 Helsinki, Finland Helsinki Univ Hosp Helsinki Finland FIN-00170 IN-00170 Helsinki, Finland Kuopio Univ Hosp, Dept Obstet & Gynecol, SF-70210 Kuopio, Finland Kuopio Univ Hosp Kuopio Finland SF-70210 necol, SF-70210 Kuopio, Finland
Titolo Testata:
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
fascicolo: 1, volume: 18, anno: 2001,
pagine: 18 - 22
SICI:
0960-7692(200107)18:1<18:FNTANC>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
NORMAL FETUSES; GESTATION; DEFECTS; HEART; THICKNESS;
Keywords:
nuchal translucency; congenital heart disease; sonography; screening;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
17
Recensione:
Indirizzi per estratti:
Indirizzo: Hiippala, A PL 281, HUS 00029, Finland PL 281 HUS Finland 00029PL 281, HUS 00029, Finland
Citazione:
A. Hiippala et al., "Fetal nuchal translucency and normal chromosomes: a long-term follow-up study", ULTRASOUN O, 18(1), 2001, pp. 18-22

Abstract

Objective To assess the impact of increased nuchal translucency observed during early pregnancy on the subsequent health of children with normal chromosomes, with special attention to cardiac anatomy and function. Methods Clinical examination and detailed cardiac evaluation were carried out in 50 chromosomally normal children at the age of 2.4-7.1 years who hadhad a nuchal translucency measurement of greater than or equal to 3 mm at 13-15 weeks' gestation. The data of two babies who died of heart defects were also included. Results Major cardiac defects were identified in four (8%) of the children. The growth of all children was within normal limits. One child had Noonansyndrome, one had a cleidocranial dysplasia and a third had a developmental delay together with an unrecognized syndrome. Webs in the neck region were noticed in two children, with no associated pathology. Conclusions In chromosomally normal fetuses with increased nuchal translucency, fetal echocardiography is necessary to identify major cardiac defects. In general, the parents can be reassured that, in the great majority, postnatal development is normal.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 06:24:29