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Titolo:
SPECT in periodic lateralized epileptiform discharges (PLEDs): a form of partial status epilepticus?
Autore:
Assal, F; Papazyan, JP; Slosman, DO; Jallon, P; Goerres, GW;
Indirizzi:
Univ Hosp Geneva, EEG Unit, Geneva, Switzerland Univ Hosp Geneva Geneva Switzerland neva, EEG Unit, Geneva, Switzerland Univ Hosp Geneva, Div Nucl Med, Geneva, Switzerland Univ Hosp Geneva Geneva Switzerland , Div Nucl Med, Geneva, Switzerland Univ Zurich Hosp, Div Nucl Med, CH-8091 Zurich, Switzerland Univ Zurich Hosp Zurich Switzerland CH-8091 CH-8091 Zurich, Switzerland
Titolo Testata:
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
fascicolo: 4, volume: 10, anno: 2001,
pagine: 260 - 264
SICI:
1059-1311(200106)10:4<260:SIPLED>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
CLINICAL-SIGNIFICANCE; EEG PATTERNS; PERFUSION; SEIZURES;
Keywords:
periodic lateralized epileptiform discharges (PLEDs); status epilepticus; SPECT; regional cerebral blood flow (rCBF);
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Assal, F Univ Calif Los Angeles, Dept Neurol, Alzheimers Dis Ctr, 710 Westwood Plaza, Los Angeles, CA 90095 USA Univ Calif Los Angeles 710 Westwood Plaza Los Angeles CA USA 90095
Citazione:
F. Assal et al., "SPECT in periodic lateralized epileptiform discharges (PLEDs): a form of partial status epilepticus?", SEIZURE-E J, 10(4), 2001, pp. 260-264

Abstract

Periodic lateralized epileptiform discharges (PLEDs) are a well defined electroencephalographic entity but whether PLEDs represent an ictal conditionor not remains debated. Much work has been done using electroencephalography (EEG) but new approaches using cerebral perfusion imaging may give more information about this question. We aimed to evaluate if PLEDs were associated with high regional cerebral blood flow (rCBF). We studied 18 patients with PLEDs and different pathologies, and performedbrain single-photon-emission computed tomography (SPECT) during and, for three cases, after the disappearance of PLEDs. Qualitative variations and locations of rCBF were compared with PLEDs. Association with seizures and type of seizures were also assessed. SPECT showed high rCBF in 18/18 patients (100%). The location of PLEDs andhigh rCBF matched in 17/18 cases (94%). In the three cases where SPECT wasperformed after PLEDs disappeared, the high rCBF had cleared (100%). Eighteen cases (100%) presented seizures before recording of PLEDs, mainly motor(partial motor or generalized tonic-clonic). Where there was a decreased rCBF (related to a lesion) there was little relationship to PLEDs and all patients with decreased rCBF had an adjacent increased rCBF These results confirm preliminary case reports. Hyperperfusionadds further to the argument that PLEDs may be related to a form of partial status epilepticus. (C) 2001 BEA Trading Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 17:25:26