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Titolo:
Cyclosporine-associated post-partum haemolytic uraemic syndrome in a renaltransplant patient: lack of response to plasmapheresis but remission afterintravenous immunoglobulin G
Autore:
Bastani, B; Mistry, BM; Jamal, JA; Contis, J;
Indirizzi:
St Louis Univ, Hlth Sci Ctr, Dept Nephrol, Div Nephrol, St Louis, MO 63110USA St Louis Univ St Louis MO USA 63110 l, Div Nephrol, St Louis, MO 63110USA St Louis Univ, Hlth Sci Ctr, Div Abdominal Organ Transplantat, St Louis, MO 63110 USA St Louis Univ St Louis MO USA 63110 Transplantat, St Louis, MO 63110 USA
Titolo Testata:
NEPHROLOGY
fascicolo: 3, volume: 6, anno: 2001,
pagine: 133 - 137
SICI:
1320-5358(200106)6:3<133:CPHUSI>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEMOLYTIC-UREMIC SYNDROME; THROMBOTIC THROMBOCYTOPENIC PURPURA; PLASMA-EXCHANGE; OKT3 THERAPY; RECIPIENTS; MICROANGIOPATHY; MANAGEMENT; PREGNANCY; ANEMIA;
Keywords:
cyclosporine; haemolytic uraemic syndrome; immunoglobulin G; plasmapheresis; post-partum haemolytic uraemic syndrome; preeclampsia; transplantation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Bastani, B St Louis Univ, Hlth Sci Ctr, Dept Nephrol, Div Nephrol, 3635 Vista Ave,FDT-9N, St Louis, MO 63110 USA St Louis Univ 3635 Vista Ave,FDT-9N St Louis MO USA 63110 0 USA
Citazione:
B. Bastani et al., "Cyclosporine-associated post-partum haemolytic uraemic syndrome in a renaltransplant patient: lack of response to plasmapheresis but remission afterintravenous immunoglobulin G", NEPHROLOGY, 6(3), 2001, pp. 133-137

Abstract

We present the case of a young woman who developed severe post-partum (cyclosporine-associated) haemolytic uraemic syndrome (HUS) 6 years after a living related donor kidney transplant. Her pregnancy had become complicated with preeclampsia (hypertension and nephrotic syndrome) and progressive renal insufficiency extending for 1 month after delivery, and there was evidence of cyclosporine vasculopathy on a kidney biopsy. Despite six daily treatments with plasmapheresis and fresh-frozen plasma replacement, her HUS progressively deteriorated, culminating in severe pulmonary haemorrhage. At thispoint, treatment with i.v. infusion of immunoglobulin G was initiated, which resulted in resolution of HUS. Moreover, at the time of diagnosis of HUSthe patient was taken off cyclosporine and maintained on mycophenolate mofetil and prednisone.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/06/20 alle ore 09:44:08