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Titolo:
Metabolic complications of HIV-1 antiretroviral therapy: The lipodystrophysyndrome
Autore:
Borderi, M; Verucchi, G; Tadolini, M; Spinosa, S; Fortunato, L; Talo, S; Chiodo, F;
Indirizzi:
Univ Bologna, Infect Dis Sect, Dept Clin & Expt Med, I-40138 Bologna, Italy Univ Bologna Bologna Italy I-40138 in & Expt Med, I-40138 Bologna, Italy
Titolo Testata:
MICROBIOLOGICA
fascicolo: 3, volume: 24, anno: 2001,
pagine: 303 - 315
SICI:
1121-7138(200107)24:3<303:MCOHAT>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
REVERSE-TRANSCRIPTASE INHIBITORS; FAT REDISTRIBUTION SYNDROME; PSEUDO-CUSHINGS-SYNDROME; GROWTH-HORMONE IMPROVES; PROTEASE INHIBITORS; BODY-COMPOSITION; FASTING HYPERINSULINEMIA; MITOCHONDRIAL TOXICITY; LIPID ABNORMALITIES; NUCLEOSIDE ANALOGS;
Keywords:
HIV-1 infection; antiretroviral therapy; lipodystrophy syndrome;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
76
Recensione:
Indirizzi per estratti:
Indirizzo: Borderi, M Univ Bologna, Infect Dis Sect, Dept Clin & Expt Med, Massarenti9, I-40138Bologna, Italy Univ Bologna Massarenti 9 Bologna Italy I-40138 Bologna, Italy
Citazione:
M. Borderi et al., "Metabolic complications of HIV-1 antiretroviral therapy: The lipodystrophysyndrome", MICROBIOLO, 24(3), 2001, pp. 303-315

Abstract

The lipodystrophy syndrome is one of the complications reported with increased frequency in patients with HIV-1 infection receiving antiretroviral therapy. The wide range of prevalence estimates may be due to differing definitions, methods and patient populations. We described the various pathogenic theories and the morphological and metabolic alterations associated with this syndrome. Even if no effective treatment exists, a correct lifestyle, adequate diet and physical exercise seem to be very important. Moreover drug therapies should be used with care to avoid potentially harmful interactions with antiretroviral agents. Ideally, the future effort to define the mechanism of lipodystrophy would be multidisciplinary and would involve not only experts in AIDS research but also nutritionists, endocrinologists and cardiologists.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 07/04/20 alle ore 03:52:19